Non-surgical treatment of adults with chronic diffuse sclerosing osteomyelitis/tendoperiostitis of the mandible

Publication date: Available online 29 November 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Marieke M. van de Meent, Miranda J.M. Wetselaar-Glas, Marta Fiocco, Natasha M. Appelman-Dijkstra, J.P.Richard van MerkesteynSummaryNon-surgical therapy has proved to be effective in chronic diffuse sclerosing osteomyelitis (DSO) of the mandible in children. Therefore we aimed to investigate the effect of non-surgical therapy in adult DSO patients.We included consecutive patients with DSO who received non-surgical therapy in our center. They all received occlusal splint therapy, counselling about the disease, and/or physiotherapy by a specialised team. The use of analgesics, preferably nonsteroidal anti-inflammatory drugs, was advised for symptomatic control during periods of exacerbation.Sixteen patients (11/5 female/male) aged 39.9 ±15.0 years with DSO of the mandible were included. The mean duration of symptoms was 39.7 ±26.3 months before referral to our center. Patients were treated with a broad range of treatments before referral. All patients underwent non-surgical treatment. In 12 patients this led to remission. Four patients still had complaints after 12 months of non-surgical therapy and started with intravenous bisphosphonate therapy.In our center, DSO of the mandible was successfully treated with non-surgical therapy, despite a long duration before referral and extensive pre-treatment. Considering this high success rate, we recommend this non-s...
Source: Journal of Cranio Maxillofacial Surgery - Category: ENT & OMF Source Type: research

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