Physical Activity and Exercise in Lung Cancer Care: Will Promises Be Fulfilled?

Physical Activity and Exercise in Lung Cancer Care: Will Promises Be Fulfilled? Oncologist. 2019 Nov 26;: Authors: Avancini A, Sartori G, Gkountakos A, Casali M, Trestini I, Tregnago D, Bria E, Jones LW, Milella M, Lanza M, Pilotto S Abstract Lung cancer remains the leading cause of cancer-related death worldwide. Affected patients frequently experience debilitating disease-related symptoms, including dyspnea, cough, fatigue, anxiety, depression, insomnia, and pain, despite the progresses achieved in term of treatment efficacy.Physical activity and exercise are nonpharmacological interventions that have been shown to improve fatigue, quality of life, cardiorespiratory fitness, pulmonary function, muscle mass and strength, and psychological status in patients with lung cancer. Moreover, physical fitness levels, especially cardiorespiratory endurance and muscular strength, are demonstrated to be independent predictors of survival. Nevertheless, patients with lung cancer frequently present insufficient levels of physical activity and exercise, and these may contribute to quality of life impairment, reduction in functional capacity with skeletal muscle atrophy or weakness, and worsening of symptoms, particularly dyspnea.The molecular bases underlying the potential impact of exercise on the fitness and treatment outcome of patients with lung cancer are still elusive. Counteracting specific cancer cells' acquired capabilities (hallmarks of cancer), together wi...
Source: The Oncologist - Category: Cancer & Oncology Authors: Tags: Oncologist Source Type: research

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Authors: Fournier E Abstract Carpal tunnel syndrome (CTS) is too common a condition not to daily interact with the practitioner, if only because of its entanglement to other pathologies, causal or chance association. The typical symptomatology, with hand paresthesia and morning pain upon waking, is related to a median nerve injury in the confined space of the carpal tunnel, more often by local inflammation and tenosynovitis of the finger flexors (repetitive activity of the hands). SCC may be secondary to situations (pregnancy) or conditions (edema, hypothyroidism…), which exaggerate the ordinary pathophysiol...
Source: Revue de Medecine Interne - Category: Internal Medicine Tags: Rev Med Interne Source Type: research
Publication date: April 2020Source: Colloids and Surfaces B: Biointerfaces, Volume 188Author(s): Didem Cetin, Meltem Okan, Erhan Bat, Haluk KulahAbstractDetection of circulating tumor cells (CTCs) from the bloodstream holds great importance to diagnose cancer at early stages. However, CTCs being extremely rare in blood makes them difficult to reach. In this paper, we introduced different surface modification techniques for the enrichment and detection of MCF-7 in microfluidic biosensor applications using gold surface and EpCAM antibody. Mainly, two different mechanisms were employed to immobilize the antibodies; covalent b...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
Publication date: 25 March 2020Source: Journal of Industrial and Engineering Chemistry, Volume 83Author(s): Xuan Thang Cao, Maheshkumar Prakash Patil, Quoc Thang Phan, Cuong M.Q. Le, Byung-Hyun Ahn, Gun-Do Kim, Kwon Taek LimAbstractThis paper reports a green and direct functionalization of poly(ethylene glycol)-graft-[furfuryl-graft-(poly(styrene-alt-maleic anhydride))] (PEG-PSMF) on the surface of single walled carbon nanotubes (SWCNTs) in aqueous media through Diels-Alder (DA) click reaction. Firstly, novel PEG grafted, furfuryl functionalized copolymers were prepared by RAFT polymerization followed by ring opening react...
Source: Journal of Industrial and Engineering Chemistry - Category: Chemistry Source Type: research
Publication date: Available online 25 January 2020Source: Colloids and Surfaces A: Physicochemical and Engineering AspectsAuthor(s): Yan Li, Shuai Wang, Fang Xiang Song, Li Zhang, Wei Yang, Hong Xia Wang, Qian Lin ChenAbstractMesoporous silica nanoparticles with folic acid (MSN-COOH-Tet-HBP-FA) are able to mediate targeting and have a pH stimulation response character, and therefore have been successfully synthesized as vectors for antitumor drug delivery. The model drug is tetrandrine (Tet). The chemical structure and properties of these NPs were characterized through systematic characterization analyses. Their drug loadi...
Source: Colloids and Surfaces A: Physicochemical and Engineering Aspects - Category: Chemistry Source Type: research
New J. Chem., 2020, Accepted Manuscript DOI: 10.1039/C9NJ05860E, PaperFan Gao, Fei Wang, Xuan Nie, Ze Zhang, Guang Chen, Lei Xia, Long-Hai Wang, Chang-Hui Wang, Zong-Yao Hao, Wen-Jian Zhang, Chun-Yan Hong, Ye-Zi You Mitochondrial malfunction is considered to be a decisive signal of apoptosis. It would be a promising strategy to target mitochondria in cancer cells to generate reactive oxygen species (ROS) directly... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - New J. Chem. latest articles - Category: Chemistry Authors: Source Type: research
Publication date: Available online 25 January 2020Source: Journal of Vascular Surgery: Venous and Lymphatic DisordersAuthor(s): Steven M. Dean, Elizabeth Valenti, Karen Hock, Julie Leffler, Amy Compston, William T. AbrahamAbstractBackgroundLower extremity lymphedema is frequently encountered in the vascular clinic. Established dogma purports that cancer is the most common cause of lower extremity lymphedema in Western countries, whereas chronic venous insufficiency (CVI) is often overlooked as a potential cause. Moreover, lymphedema is typically ascribed to a single cause, yet multiple causes can coexist.MethodsA 3-year re...
Source: Journal of Vascular Surgery: Venous and Lymphatic Disorders - Category: Surgery Source Type: research
Publication date: Available online 25 January 2020Source: Journal of Advanced ResearchAuthor(s): Bing Wei, Fei Dong, Wei Yang, Chunhua Luo, Qiujing Dong, Zuoqin Zhou, Zheng Yang, Liangquan ShengAbstractFor facilitating theranostic nanoplatform with multimodal therapeutic ability, we develop the core-shell structured CDs@SiO2@TiO2 nanoplatforms (CST NPs). The designed CST NPs possess excellent photothermal effect and fluorescence resonance energy transfer (FRET) induced photodynamic property, which could achieve synergistic photothermal and photodynamic therapy. Meanwhile, the photothermal ability of CST NPs acts as a key r...
Source: Journal of Advanced Research - Category: Research Source Type: research
Scott J. Davidoff, M.D. - Main Line Spine Scott J. Davidoff, M.D. is a physician at Main Line Spine who specializes in physical medicine, pain medicine, and sports medicine. mainlinespine.com i'm posting the bio of this physician simply for illustrative purposes. this group for example has a bunch of the docs there who have done a fellowship at a number of non accredited places yet they are all saying they are board certified and this person is even the president of american board of pain? how can someone be the president of the board when doing a ...
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
ConclusionOur results suggest improved detection of PCa with similar PPV and confidence scores when higher TE values are utilized for T2-weighted image acquisition.
Source: Academic Radiology - Category: Radiology Source Type: research
Publication date: Available online 25 January 2020Source: Social Science &MedicineAuthor(s): Katherine TierneyAbstractRacial disparities in outcomes of assisted reproductive technologies (ART) are well-documented, and evidence of racial disparities in other forms of fertility treatments has also been observed. To date, much of the research on these disparities has focused on individual-level causes. This paper contextualizes these disparities using the weathering hypothesis. Using the National Survey of Family Growth and exploratory analyses of the National Health and Nutrition Examination Survey, this study evaluates ...
Source: Social Science and Medicine - Category: Psychiatry & Psychology Source Type: research
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