Comparative immunology: allorecognition and variable surface receptors outside the jawed vertebrates.
Comparative immunology: allorecognition and variable surface receptors outside the jawed vertebrates.
Curr Opin Immunol. 2013 Jul 24;
Authors: Dionne MS
Abstract
Allograft rejection is one of several undesirable consequences of the adaptive nature of the mammalian immune response. This review examines adaptive immune responses and allorecognition in animals with very different immune responses - jawless vertebrates, arthropods, and two distinct colonial marine invertebrates - with the goal of understanding how immune adaptation and allograft rejection are linked, and conversely how a system works where allograft rejection is a desired outcome rather than an unforeseen consequence.
PMID: 23890586 [PubMed - as supplied by publisher]
Source: Current Opinion in Immunology - Category: Allergy & Immunology Authors: Dionne MS Tags: Curr Opin Immunol Source Type: research
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