Comparative immunology: allorecognition and variable surface receptors outside the jawed vertebrates.
Comparative immunology: allorecognition and variable surface receptors outside the jawed vertebrates. Curr Opin Immunol. 2013 Jul 24; Authors: Dionne MS Abstract Allograft rejection is one of several undesirable consequences of the adaptive nature of the mammalian immune response. This review examines adaptive immune responses and allorecognition in animals with very different immune responses - jawless vertebrates, arthropods, and two distinct colonial marine invertebrates - with the goal of understanding how immune adaptation and allograft rejection are linked, and conversely how a system works where allograft rejection is a desired outcome rather than an unforeseen consequence. PMID: 23890586 [PubMed - as supplied by publisher]
This article tracks this technological growth so that surgeons may better serve their patients in treating spine-related pain and disability.
In conclusion, we propose the repurposing of benztropine for anticancer research and therapeutics that can suppress tumor progression, CTC, and metastasis of aggressive cancers by reducing key pro-tumorigenic factors.
Authors: Shehadeh AM, Isleem U, Abdelal S, Salameh H, Abdelhalim M Abstract Background: Joint-sparing limb salvage surgery (JSLSS) is an advancement in the techniques and concepts of limb salvage surgery, which makes it possible to save not only the limb affected by malignancy but also the adjacent joint and the epiphyseal plate. In the growing child, this procedure is technically demanding due to the availability of small length of bone for implant purchase. Reconstruction options can be biological reconstruction or endoprosthesis; however, the outcome of endoprosthetic reconstruction after joint-sparing resection...
Publication date: Available online 21 February 2020Source: Canadian Journal of CardiologyAuthor(s): Alexander Emmott, Vanessa Hertig, Alexandre Bergeron, Louis Villeneuve, Laurence Lefebvre, Richard L. Leask, Angelino Calderone, Ismail El-HamamsyAbstractBackgroundClinical studies have revealed a greater risk of pulmonary autograft dilatation after the Ross procedure in patients with preoperative aortic insufficiency (AI). The present study examined whether the morphological, biomechanical and cellular properties of the pulmonary artery (PA) from patients with AI were phenotypically different compared to patients diagnosed ...
Comminuted proximal humerus fractures are more frequently being treated utilizing an intramedullary fibular strut allograft to assist with open reduction internal fixation. Although this technique has led to improved outcomes, avascular necrosis, rotator cuff failure, and/or prominent hardware may still occur necessitating conversion to reverse shoulder arthroplasty. The presence of an intramedullary strut allograft makes this conversion technically demanding and creates certain potential complications unique to this group. This manuscript details the conversion of a proximal humerus open reduction internal fixation with a...
Unfortunately, the author Jon Olav Drogset was incorrectly published in the original version and updated here. The original article has been corrected.
CONCLUSIONS: In spite of variation with respect to their use, allograft tissue products are popular and interest in new products, especially to improve flexor tendon pulley reconstruction, is high. PMID: 32074352 [PubMed - in process]
Conclusions: For one-level ACDF, the anchored cage with screws has some advantage compared to the stand-alone PEEK cage in avoiding dysphagia and restoring disc space height and cervical lordosis. We suggest the anchored spacer may be a good substitute for the stand-alone cage in one-level ACDF. Level of Evidence: Level II
Publication date: Available online 19 February 2020Source: Journal of Evidence Based Dental PracticeAuthor(s): Lubomyr Ravlyk, Sukaynah Alawami, Thikriat Al-Jewair
ConclusionsGTR of intrabony defects in AgP with either standard or modified CM yielded similarly successful and maintainable clinical benefits for compromised teeth 4 years following the surgery. The use of MPM showed no additional benefit.Clinical relevanceThis study demonstrates that most of the positive outcomes of GTR in AgP may be preserved over 4 years. Periodontitis recurrence might influence long-term outcomes.