Increased β-Lactams dosing regimens improve clinical outcome in critically ill patients with augmented renal clearance treated for a first episode of hospital or ventilator-acquired pneumonia: a before and after study

Augmented renal clearance (ARC) is recognized as a leading cause of β-lactam subexposure when conventional dosing regimens are used. The main objective was to compare the clinical outcome of ARC patients treat...
Source: Critical Care - Category: Intensive Care Authors: Tags: Research Source Type: research

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BOSTON (CBS) – Two people in New Hampshire are undergoing testing for novel coronavirus. Health officials say the two people recently traveled to Wuhan City, China and developed respiratory symptoms. “These people have more mild illness, but both sought healthcare for their illnesses and are recovering,” the New Hampshire Department of Health and Human Services said. “They remain isolated until test results are available.” On Thursday, a student from White Mountain School in Bethlehem went to the emergency room at Littleton Regional Healthcare with mild flu-like symptoms. The student had trave...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Syndicated CBSN Boston Syndicated Local Coronavirus New Hampshire Source Type: news
The U.S. Food and Drug Administration (FDA) outlined steps it plans to take...Read more on AuntMinnie.comRelated Reading: Abnormal chest CT findings anchor coronavirus outbreak X-ray, CT uncover novel coronavirus-infected pneumonia FDA to host workshop on medical applications of AR, VR FDA finalizes easier rules for CADe software Carestream wins FDA clearance for tomosynthesis
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
The U.S. Centers for Disease Control and Prevention has confirmed five cases of a SARS-like form of coronavirus in the U.S. On Tuesday, Chinese officials announced 25 additional deaths from the infection, raising the death toll to 106. The disease, which is believed to have originated in a seafood market in the Chinese central city of Wuhan, has infected a few thousand people across China and has also spread to other countries. Chinese officials have confirmed more than 4,400 cases of the novel coronavirus nationwide and more than 2,700 cases in Hubei, the province where Wuhan is located, according to a virus tracker maint...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized China Infectious Disease onetime overnight Source Type: news
Logan Airport screened one flight from Hong Kong and local hospitals are taking a number of other precautions in the midst of a national coronavirus outbreak.   The state does not have a single confirmed case of the virus, which presents as mild to moderate upper-respiratory tract illnesses and sometimes lower-respiratory tract illnesses, such as pneumonia or bronchitis. Yet public health officials and state legislators are preparing should the state en counter a case.  The Department of Public…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Condition:   Ventilator-associated Pneumonia Interventions:   Device: ETTEvac;   Device: BIP ETTEvac Sponsor:   Bactiguard AB Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
In conclusion, advance directives are important to avoid unwanted medical interventions, including simple interventions to address life-threatening conditions. But advance directives cannot preclude someone from entering dementia—to do that, one needs to consider VSED while having capacity. At the point of dementia, standard of care comfort care, with an appropriate strategy of feeding, should be provided.  
Source: blog.bioethics.net - Category: Medical Ethics Authors: Tags: End of Life Care Health Care advance directives Author: Shelton dementia syndicated Source Type: blogs
(BEIJING) — A new viral illness being watched with a wary eye around the globe accelerated its spread in China with 80 deaths so far, while the U.S. Consulate in the city at the epicenter announced it will evacuate its personnel and some other Americans aboard a charter flight. China’s health minister said the country was entering a “crucial stage” as “it seems like the ability of the virus to spread is getting stronger.” Ma Xiaowei declined to estimate how long it would take to bring the situation under control, but said travel restrictions and other strict measures should bring results...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized China Infectious Disease onetime overnight Source Type: news
In this study we have genetically modified a serotype 1 strain (519/43), the first time that this has been achieved for this serotype, providing the methodology for a deeper understanding of its biology and pathogenicity. As proof of principle we constructed a defined pneumolysin mutant and showed that it lost its ability to lyse red blood cells. We also showed that when mice were infected intranasally with the mutant 519/43Δply there was no significant difference between the load of bacteria in lungs and blood when compared to the wild type 519/43. When mice were infected intraperitoneally there were significantly f...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
This study represents the first large scale attempt to gather a long period information on Q fever infection in Greece. The findings of the current study support the fact that Q fever is an important endemic zoonotic disease in Greece and needs increased awareness by clinical physicians and health care system.
Source: Comparative Immunology, Microbiology and Infectious Diseases - Category: Infectious Diseases Source Type: research
AbstractHuntington ’s disease (HD) is a rare neurodegenerative disorder of the central nervous system characterized by involuntary choreatic movements, cognitive, behavioral, and psychiatric disturbances. Most HD suffer from dysphagia and aspiration pneumonia is the leading cause of death. However, little is known a bout dysphagia management in HD. A revision of the literature was conducted to depict the state of the art on the assessment and treatment of dysphagia in HD. Literature search of the last 10 years was performed using PubMed and EMBASE. Twenty-four studies were included: 16 cross-sectional studies, 2...
Source: Neurological Sciences - Category: Neurology Source Type: research
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