Major NHS hospital sees record 499 A&E patients in one 'manic' day

The Royal Stoke University Hospital (pictured) in Stoke-on-Trent, saw 155 children on Sunday - double the usual amount - and said a flu-like illness was to blame for many visits.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Publication date: January 2020Source: The Annals of Thoracic Surgery, Volume 109, Issue 1Author(s): Elisabetta Lapenna, Michele De Bonis, Ilaria Giambuzzi, Benedetto Del Forno, Stefania Ruggeri, Manuela Cireddu, Simone Gulletta, Alessandro Castiglioni, Ottavio Alfieri, Paolo Della Bella, Stefano BenussiBackgroundThe study sought to assess the long-term outcomes of the stand-alone Cox-Maze IV procedure in symptomatic patients with refractory, persistent, or long-standing persistent atrial fibrillation (AF).MethodsFifty-nine consecutive patients (mean age 52 ± 10.5 years, previous catheter ablation 80%, left ventricul...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
This study included 243 youths, ages 12 to 25 years (42 healthy controls, 43 non–help-seeking individuals [stage 0], 52 help-seeking youth experiencing distress and possibly mild symptoms of anxiety or depression [stage1a], and 108 youth demonstrating attenuated symptoms of an SMI such as bipolar disorder or psychosis [stage 1b]). Participants completed an adapted version of the Childhood Trauma and Abuse scale. There were high frequencies of reported trauma across all stages. Symptomatic individuals experienced more trauma and bullying. Stage 1b individuals reported more physical abuse. Stage 1b also indicated psych...
Source: The Journal of Nervous and Mental Disease - Category: Psychiatry Tags: Original Articles Source Type: research
To investigate which factors individuals with a psychotic depression experience as preventive of suicide while beeing hospitalized. Semi-structured qualitative interviews with nine inpatients, all hospitalized for a unipolar or bipolar depressive episode w...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news
It takes an average of seven years for people who have some, but not all, symptoms of obsessive-compulsive disorder (subthreshold OCD) to develop full-blown OCD, according to astudyin theJournal of Affective Disorders. The study also suggests that certain characteristics, such as male sex, the presence of other psychiatric conditions, and romantic status, may be associated with a faster transition from subthreshold OCD to OCD.Emma M. Thompson, a Ph.D. candidate at Monash University in Australia, and colleagues examined data from 954 patients who were enrolled in treatment centers in the Brazilian Research Consortium on Obs...
Source: Psychiatr News - Category: Psychiatry Tags: Emma Thompson Journal of Affective Disorders Monash University obsessive-compulsive disorder subthreshold OCD Source Type: research
Publication date: Available online 13 December 2019Source: Journal of Membrane ScienceAuthor(s): So Young Lee, Ji Eon Chae, Jieun Choi, Hyun Seo Park, Dirk Henkensmeier, Sung Jong Yoo, Jin Young Kim, Youngseung Na, Jong Hyun Jang, Hyoung-Juhn KimAbstractTo realize effective polymer electrolyte fuel cell (PEFC) operation under non-humidified conditions, a new self-humidifying dual exchange membrane fuel cell (DEMFC) was designed and evaluated. The DEMFC was fabricated using sequentially aligned membrane electrode assemblies (MEAs) consisting of an anion exchange membrane (AEM) and a cation exchange membrane (CEM). In this s...
Source: Journal of Membrane Science - Category: Materials Science Source Type: research
Publication date: 12 December 2019Source: Cell, Volume 179, Issue 7Author(s): Cross-Disorder Group of the Psychiatric Genomics ConsortiumSummaryGenetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci. However, the nature and mechanisms of these pleiotropic effects remain unclear. We performed analyses of 232,964 cases and 494,162 controls from genome-wide studies of anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, and Tourette synd...
Source: Cell - Category: Cytology Source Type: research
Conclusion: The CACNA1C polymorphism rs1006737 is associated with the mean thickness of cortical brain areas that have been shown to be altered in bipolar disorder. PMID: 31829002 [PubMed - as supplied by publisher]
Source: Journal of Psychiatry and Neuroscience - Category: Psychiatry Tags: J Psychiatry Neurosci Source Type: research
Authors: Palmier-Claus J, Wright K, Mansell W, Bowe S, Lobban F, Tyler E, Lodge C, Jones S Abstract Behavioural experiments are an important component of cognitive behavioural therapy. However, there exists little up-to-date guidance on how to conduct these in people with a diagnosis of bipolar disorder. This paper provides recommendations on how to conduct behavioural experiments in people with bipolar disorder. The aim is to upskill and empower clinicians to conduct behavioural experiments. The paper combines the expertise of senior clinicians working in the United Kingdom. The article starts by providing general...
Source: Clinical Psychology and Psychotherapy - Category: Psychiatry Tags: Clin Psychol Psychother Source Type: research
Green Chem., 2020, Advance Article DOI: 10.1039/C9GC02460C, PaperWei-Ting Gao, Qing Chen, Ming-Gu Du, Wei-Ming Zhang, Chang-Yan Cao, Wei-Guo Song Along with catalytic hydrogenation, producing pure chiral amino alcohols with a perfect atom economy is achieved by electrodialysis with bipolar membranes. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Green Chem. latest articles - Category: Chemistry Authors: Source Type: research
Excitatory amino acid transporter 2 (EAAT2) is the predominant astrocyte glutamate transporter involved in the reuptake of the majority of the synaptic glutamate in the mammalian central nervous system (CNS). Gene expression can be altered without changing DNA sequences through epigenetic mechanisms. Mechanisms of epigenetic regulation, include DNA methylation, post-translational modifications of histones, chromatin remodeling, and small non-coding RNAs. This review is focused on neurological disorders, such as glioblastoma multiforme (GBM), Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS), Parkinson&rsq...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
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