Sepsis induced cardiomyopathy: Pathophysiology and use of mechanical circulatory support for refractory shock

Sepsis remains a major cause of morbidity and mortality, and sepsis-induced cardiomyopathy (SCM) has been recognized as a relevant complication. In this article, the pathophysiology of SCM and the literature regarding the clinical care with a focus on the use of mechanical circulatory support for the rescue of patients with severe SCM are reviewed. Lastly, a pragmatic approach to the care of this complex patient population is provided using a representative case example.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news

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Conclusion: The spatial QRS-T angle and Twvm are emerging VCG indices which are independently associated with mortality in patients with reduced left ventricular ejection fraction due to ICMP or NICMP. Using a composite score of all 3 vector indices, a maximum score was associated with poor long-term survival.Cardiology
Source: Cardiology - Category: Cardiology Source Type: research
Publication date: Available online 19 September 2020Source: Revista Española de Cardiología (English Edition)Author(s): Chia Siang Kow, Syed Shahzad Hasan
Source: Revista Espanola de Cardiologia - Category: Cardiology Source Type: research
AbstractObjectiveAtrial functional mitral regurgitation (AFMR) is caused by atrial fibrillation and left atrial enlargement. Our study aimed to evaluate the efficacy of left atrial plication (LAP) for AFMR.MethodsOf 1164 mitral valve surgery patients at our hospital from January 2000 to May 2019, 22 patients underwent surgery for AFMR. Our retrospective analysis divided the patients with AFMR into two groups according to whether LAP was performed (LAP  + group,n = 9; LAP − group,n = 13). Mitral valve angle (MV angle) (horizontal inclination of mitral valve) was ...
Source: General Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
We describe a TM programme in this population and evaluate its effectiveness during a 12 month period.Methods and resultsWe conducted a single ‐centre study of patients discharged from hospital after decompensated HF, allocated into three groups: prospective TM programme, prospective HF protocol follow‐up programme (PFP) with no TM facilities, and retrospective propensity‐matched usual care (UC). TM effectiveness was assessed by all‐ cause hospitalizations and mortality; HF‐related hospitalization (HFH), days lost to unplanned hospital admissions/death, functional capacity and quality of life (New York Heart...
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Original Research Article Source Type: research
Systolic anterior motion of the mitral valve (SAM) first was described in the 1960s in patients with hypertrophic cardiomyopathy, and later following mitral valve (MV) annuloplasty, in the 1970s.1,2 Since then, it has been shown that left ventricular outflow tract obstruction (LVOTO) from SAM has a plethora of other predisposing risk factors. These risk factors include, but are not limited to, hypertrophic cardiomyopathy, anterior and medial displacement of the left ventricular papillary muscles, redundant MV leaflet tissue, and after mitral valve repair (MVR) and aortic valve replacement (AVR) surgeries.
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Editorial Source Type: research
CONCLUSIONS This work provides a useful method to increase coronary perfusion and may be beneficial for improving myocardial function in patients with end-stage heart failure, especially those with ischemic cardiomyopathy (ICM). PMID: 32940255 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Authors: Angelini C, Marozzo R, Pegoraro V, Sacconi S Abstract INTRODUCTION: Metabolic myopathies comprise a clinically etiological diverse group of disorders caused by defects in cellular energy metabolism including the breakdown of carbohydrates and fatty acids, which include glycogen storage diseases and fatty acid oxidation disorders. Their wide clinical spectrum ranges from infantile severe multisystemic disorders to adult-onset myopathies. To suspect in adults these disorders, clinical features such as exercise intolerance and recurrent myoglobinuria need investigation while another group presents fixed weakness...
Source: Expert Review of Neurotherapeutics - Category: Neurology Tags: Expert Rev Neurother Source Type: research
PMID: 32929710 [PubMed - in process]
Source: Cardiology Journal - Category: Cardiology Authors: Tags: Cardiol J Source Type: research
Left atrial (LA) function plays an important role in diastolic dysfunction in cats with hypertrophic cardiomyopathy (HCM). Two-dimensional speckle tracking echocardiography (2D-STE) is a technique for assessin...
Source: BMC Veterinary Research - Category: Veterinary Research Authors: Tags: Research article Source Type: research
AbstractATTR amyloidosis is caused by systemic deposition of transthyretin (TTR) and comprises ATTRwt (wt for wild-type) amyloidosis, ATTRv (v for variant) amyloidosis, and acquired ATTR amyloidosis after domino liver transplantation. ATTRwt amyloidosis has classically been regarded as cardiomyopathy found in the elderly, whereas carpal tunnel syndrome has also become a major initial manifestation. The phenotypes of ATTRv amyloidosis are diverse and include neuropathy, cardiomyopathy, and oculoleptomeningeal involvement as the predominant features, depending on the mutation and age of onset. In addition to variant TTR, the...
Source: Neurology and Therapy - Category: Neurology Source Type: research
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