Medical News Today: Extra virgin olive oil may protect against various dementias

A new study in mice finds that extra virgin olive oil prevents the toxic accumulation of tau protein in the brain and keeps memory intact.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Alzheimer's / Dementia Source Type: news

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Intercellular propagation of protein aggregation is emerging as a key mechanism in the progression of several neurodegenerative diseases, including Alzheimer's disease and frontotemporal dementia (FTD). However, we lack a systematic understanding of the cellular pathways controlling prion-like propagation of aggregation. To uncover such pathways, here we performed CRISPR interference (CRISPRi) screens in a human cell-based model of propagation of tau aggregation monitored by FRET. Our screens uncovered that knockdown of several components of the endosomal sorting complexes required for transport (ESCRT) machinery, includin...
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: Editors ' Picks Source Type: research
In a mouse study, researchers have tested the potential of a ketone ester-rich diet in slowing down Alzheimer's, and have found this approach promising.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Alzheimer's / Dementia Source Type: news
Publication date: Available online 10 December 2019Source: NeuroImageAuthor(s): M. Belen Bachli, Lucas Sedeño, Jeremi K. Ochab, Olivier Piguet, Fiona Kumfor, Pablo Reyes, Teresa Torralva, María Roca, Juan Felipe Cardona, Cecilia Gonzalez Campo, Eduar Herrera, Andrea Slachevsky, Diana Matallana, Facundo Manes, Adolfo M. García, Agustín Ibáñez, Dante R. ChialvoAbstractAccurate early diagnosis of neurodegenerative diseases represents a growing challenge for current clinical practice. Promisingly, current tools can be complemented by computational decision-support methods to objectivel...
Source: NeuroImage - Category: Neuroscience Source Type: research
New research in mice and flies suggests that failure to transport molecules that break down proteins in neurons may lead to neurodegenerative diseases.
Source: Parkinson's Disease News From Medical News Today - Category: Neurology Tags: Alzheimer's / Dementia Source Type: news
New research in mice and flies suggests that failure to transport molecules that break down proteins in neurons may lead to neurodegenerative diseases.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Alzheimer's / Dementia Source Type: news
This study aims to describe the gender and age differences in the incidence and prevalence of dementia and AD in Taiwan. Methods: The data on dementia and AD were acquired from the Taiwan National Health Insurance Research Database from 2004 to 2010. The sex and age-specific rates were standardized, and the differences of gender and age on dementia or AD were assessed using Poisson regression analysis. Results: Over seven years, the prevalence of dementia and AD significantly increased from 4.7 to 7.6 per hundred people (β = 0.0784, p
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
You're reading How Does Sleeping Well Impact Brain Detoxification?, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles. Have you been sleeping well lately? We all know that getting enough sleep is an important part of living a healthy and engaged life. Of course, getting a good night's sleep keeps you sharp during the day, and recent science has also shown how important it is in learning and memory. Sleep is not only good for helping you pay attention in class or remembering what you did yesterday though, it also helps keep ...
Source: PickTheBrain | Motivation and Self Improvement - Category: Consumer Health News Authors: Tags: featured health and fitness self improvement better sleep brain health science of sleep Source Type: blogs
Source: Science Translational Medicine - Category: Biomedical Science Authors: Tags: Editorial Source Type: research
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Source: International Journal of Neuroscience - Category: Neuroscience Authors: Source Type: research
ConclusionsThis study provides information about Aβ plaque burden, tau tangle burden, and neurodegeneration in cognitively unimpaired persons at three levels of genetic risk for AD. Unimpaired APOE ϵ4 HMs can be studied before their 70s to evaluate the understanding of factors, processes, and interventions involved in the predisposition to and prevention of AD, and after their 70s, to discover factors, processes, and interventions involved in the resilience or resistance to and prevention of AD.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
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