MRI spots tumors in women with dense breasts, but false positives a problem

(Reuters Health) - Breast cancer can be difficult to detect in women with extremely dense breast tissue, but a new Dutch study indicates that getting an MRI scan can spot tumors that would otherwise be missed.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

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Last year, Vayyar Imaging, a leader in 4D imaging technology, announced its next-generation CMOS System on a Chip technology and made its first foray into remote patient monitoring with Walabot HOME. Vayyar’s latest announcement came out last w...
Source: Medgadget - Category: Medical Devices Authors: Tags: Exclusive Source Type: blogs
ConclusionsOur data suggest that the investigated brain tumors had an intact BBTB, which is impermeable to anticancer drugs, which are dual ABCB1/ABCG2 substrates. Therefore, effective drugs for antitumor treatment should have high passive permeability and lack ABCB1/ABCG2 substrate affinity.Trial registrationEuropean Union Drug Regulating Authorities Clinical Trials Database (EUDRACT), 2011-004189-13. Registered on 23 February 2012,https://www.clinicaltrialsregister.eu/ctr-search/search?query=2011-004189-13.
Source: EJNMMI Research - Category: Radiology Source Type: research
ConclusionHigh estradiol levels contribute to increasing capsular contracture caused byS. epidermidis biofilm formation.No Level AssignedThis journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authorswww.springer.com/00266.
Source: Aesthetic Plastic Surgery - Category: Cosmetic Surgery Source Type: research
SAN ANTONIO (AP) — Doctors on Wednesday reported unusually good results from tests of two experimental drugs in women with an aggressive form of breast cancer that had spread widely and resisted many previous treatments. One drug showed particular ability to reach tumors in the brain, which are notoriously tough to treat. The other pairs a sort of homing device for cancer cells with a payload of chemotherapy that’s released when it reaches its target. “It’s a guided missile. It’s able to bring the chemotherapy directly to the cancer cell,” said the study leader, Dr. Ian Krop of the Dana-...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Syndicated CBSN Boston Breast Cancer Dana Farber Cancer Institute Source Type: news
CONCLUSION: Application of the subtype-guided 18F-FDG PET/CT could accurately predict nodal response and aid in tailoring axillary surgery among patients with node-positive breast cancer after NAC, which includes identifying candidates appropriate for TAD or directly proceeding to ALND. This approach might help to avoid false-negative events in TAD. IMPLICATIONS FOR PRACTICE: This feasibility study showed that 18[F]-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) could accurately predict nodal response after neoadjuvant chemotherapy (NAC) among patients with breast cancer with in...
Source: The Oncologist - Category: Cancer & Oncology Authors: Tags: Oncologist Source Type: research
Conclusion.Performing 18F‐FES PET/CT in newly diagnosed ER‐positive breast cancer patients increases the value of diagnosis equivocal lesions and treatment management compared with 18F‐FDG PET/CT.Implications for Practice.This study investigated whether 16a‐18F‐fluoro‐17b‐estradiol (18F‐FES) positron emission tomography (PET)/computed tomography (CT) affects the clinical management of patients with newly diagnosed estrogen receptor (ER)‐positive breast cancer. Physicians completing two questionnaires comparing the clinical impact of 18F‐FES and 18F‐FDG on individual management plans in patients with n...
Source: The Oncologist - Category: Cancer & Oncology Authors: Tags: Breast Cancer Source Type: research
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Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized medicine onetime Research syndication Source Type: news
In this study we design green synthesis of a novel ZnO nanocarrier loaded with paclitaxel as a drug delivery system with high cytotoxicity against breast cancer cell line (MCF-7) and low side effects on the normal cell line (fibroblast). Paclitaxel is formulated in high concentration in Cremophor EL because of its low solubility. Zinc oxide nanoparticles (ZnO NPs) were prepared by the ethanolic extract of Camellia sinensis L., then coated with chitosan (Ch) and loaded with paclitaxel (PTX) to improve drug delivery. The physicochemical properties were observed by transmission electron microscopy (TEM), thermo-gravimetric an...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
ConclusionOur data suggest that pure 2S-[18F]FASu can be used to noninvasively image system xC- in a variety of cancers, either as the racemic mixture (2S,5R/S-) or optically pure form. Furthermore, this work shows potential utility of [18F]FASu for detection of glioblastoma and prostate cancer.
Source: Molecular Imaging and Biology - Category: Molecular Biology Source Type: research
The fiercely contested race to demonstrate how artificial intelligence (AI)...Read more on AuntMinnie.comRelated Reading: C-MIMI: AI could cut mammography workload in half AI shows promise for reducing mammography workload AI enhances radiologist performance for DBT Deep learning enhances breast cancer risk assessment SBI: AI improves DBT's performance in dense tissueComments: 12/1/2019 2:21:59 PMHospital-Rad If I were a resident I would think twice before choosing breast fellowship. Although a mammographer won't be replaced by AI completely, I predict that the work volume will decrease dramatically. Screenings...
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
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