DNA methylation-based profiling of uterine neoplasms: a novel tool to improve gynecologic cancer diagnostics.

CONCLUSION: Herein, we describe distinct DNA methylation signatures in uterine neoplasms and show that array-based DNA methylation analysis holds promise as an ancillary tool to further characterize uterine neoplasms, especially in cases which are diagnostically challenging by conventional techniques.
PMID: 31768620 [PubMed - as supplied by publisher]

Source: Methods of Information in Medicine - November 24, 2019 Category: Information Technology Authors: Kommoss FKF, Stichel D, Schrimpf D, Kriegsmann M, Tessier-Cloutier B, Talhouk A, McAlpine JN, Chang KTE, Sturm D, Pfister SM, Romero-Pérez L, Kirchner T, Grünewald TGP, Buslei R, Sinn HP, Mechtersheimer G, Schirmacher P, Schmidt D, Lehr HA, Sahm F, Hunt Tags: J Cancer Res Clin Oncol Source Type: research