A Novel Mechanism for Th17 Inflammation in Human Type 2 Diabetes Mellitus.

A Novel Mechanism for Th17 Inflammation in Human Type 2 Diabetes Mellitus.
Trends Endocrinol Metab. 2019 Nov 22;:
Authors: Kiernan K, MacIver NJ
Abstract
In their recent study, Nicholas et al. challenge the current dogma that T cell inflammation must be fueled by glycolysis and demonstrate a novel metabolic mechanism for Th17 inflammation in human type 2 diabetes mellitus (T2DM): a combination of increased environmental long-chain fatty acid metabolites coupled with decreased fatty acid oxidation.
PMID: 31767267 [PubMed - as supplied by publisher]

Source: Trends in Endocrinology and Metabolism: TEM - November 21, 2019 Category: Endocrinology Authors: Kiernan K, MacIver NJ Tags: Trends Endocrinol Metab Source Type: research