GABAergic approach of postpartum depression: A translational review of literature.

CONCLUSION: Disability to modulate GABA-A-r expression during pregnancy and restore its previous state after parturition appears to trigger PPD. The GABAergic system is a promising pharmacotherapy target. From preclinical to clinical studies for about twenty years the GABAergic system has been incriminated and targeted in this challenging mental disease. PMID: 31767256 [PubMed - as supplied by publisher]
Source: L Encephale - Category: Psychiatry Tags: Encephale Source Type: research

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ConclusionsAutistic mothers face unique challenges and the stigma associated with autism may further exacerbate communication difficulties. Greater understanding and acceptance amongst individuals who interact with autistic mothers is needed, and autistic mothers would benefit from additional and better-tailored support.
Source: Molecular Autism - Category: Molecular Biology Source Type: research
ConclusionThe research project aims to directly improve identification and support of vulnerable children across selected regions in Austria, and by doing so, improve the health and well-being of future Austrian generations while breaking the cycle of intergenerational transfer of adverse childhood experiences. The described project underwent a rigorous public review process (https://ois.lbg.ac.at/en/methods-projects/crowdsourcing-research-questions-in-science) with different stakeholders as well as people with lived experience and scientific experts of the field having reviewed our proposal (https://ois.lbg.ac.at/en/metho...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Conclusions: Sleep patterns in children and adolescents were related to the psychiatric diagnosis of their parent(s). Future follow-up of these results may clarify the relations between early sleep differences and the risk of developing mood disorders in individuals at high familial risk.IntroductionSleep disturbances are core symptoms of mood disorders including major depressive disorder and bipolar disorder (1). Additionally, sleep problems have been associated with more severe symptoms, greater functional impairment, and increased risk for relapse among individuals with mood disorders (2). Over 40% of children and youth...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Conclusions: The observed associations between BPA, MnBP, and behavior in boys are consistent with previous findings. Further health impact assessment studies based on dose–response functions corrected for exposure misclassification are required to quantify the public health burden possibly entailed by such associations. https://doi.org/10.1289/EHP1314 Received: 02 November 2016 Revised: 23 May 2017 Accepted: 19 June 2017 Published: 15 September 2017 Address correspondence to C. Philippat, Institut for Advanced Biosciences, Site Santé – Allée des Alpes, 38700 La Tronche, France. Phone: +33 4...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
Conclusion: Prenatal urinary BPA concentration was associated with some aspects of child behavior in this cohort, and some associations were stronger among boys. https://doi.org/10.1289/EHP984 Received: 18 August 2016 Revised: 09 December 2016 Accepted: 12 December 2016 Published: 16 June 2017 Address correspondence to Joseph M. Braun, Department of Epidemiology, Box G-S121-2, Brown University, Providence, RI 02912 USA. Telephone: (401) 863-5397. E-mail: joseph_braun_1@brown.edu Supplemental Material is available online (https://doi.org/10.1289/EHP984). The authors declare they have no actual or potential competing fi...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
By Susan Blumenthal, M.D. and Alexandrea Adams The recent commemoration of National Women’s Health Week provided an important time to mark the progress that has been made in advancing women’s health over the past two decades and to highlight what more needs to be done to achieve women’s health equity in America. Historically, women have experienced discrimination in health care despite making 80 percent of health care decisions for their families, using more medical services than men, and suffering greater disability from chronic disease. Before the mid 1990’s, women were often excluded as subjects ...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
House Republicans passed legislation to repeal and replace the Affordable Care Act on Thursday, slashing health care coverage for millions, capping Medicaid expansions, and potentially allowing for discrimination against individuals with pre-existing conditions ― some of which essentially amount to being a woman.  An amendment added to the Affordable Health Care Act could allow insurance companies to charge higher premiums for citizens who have experienced postpartum depression, pregnancy, a C-section, domestic violence or rape. On the same day, the House also voted to defund ...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
GENEVA (Reuters) - More than 4 percent of the world’s population lives with depression, and women, youth and the elderly are the most prone to its disabling effects, the World Health Organization (WHO) said on Thursday. An estimated 322 million people suffered depressive disorders in 2015, a rise of 18.4 percent in a decade, as people live longer, the United Nations agency said in a report. Global economic losses exceed $1 trillion a year, it said, referring to lost productivity due to apathy or lack of energy that lead to an inability to function at work or cope with daily life. “Depression is the single large...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
Conclusion: Going beyond the powerful scientific and economic arguments for urgent action to reduce the burning of fossil fuels is the strong moral imperative to protect our most vulnerable populations. Citation: Perera FP. 2017. Multiple threats to child health from fossil fuel combustion: impacts of air pollution and climate change. Environ Health Perspect 125:141–148; http://dx.doi.org/10.1289/EHP299 Address correspondence to F.P. Perera, Department of Environmental Health Sciences, Columbia Center for Children’s Environmental Health, Columbia University Mailman School of Public Health, 722 West 168th St. ...
Source: EHP Research - Category: Environmental Health Authors: Tags: Commentaries Children's Health February 2017 Source Type: research
By Sona Dimidjian and Richard Davidson Sona Dimidjian is an Associate Professor in the Department of Psychology and Neuroscience at the University of Colorado, Boulder. Her research addresses the treatment and prevention of depression, with a particular focus on the mental health of women during pregnancy and postpartum. Richard J. Davidson is a leading expert on the study of emotions and how they affect well-being. He is the founder of the Center for Healthy Minds and the William James and Vilas Professor of Psychology and Psychiatry at the University of Wisconsin - Madison. If you were told that nearly half of the pe...
Source: Science - The Huffington Post - Category: Science Source Type: news
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