Systemic Effects of Steroids Following Epidural Steroid Injections

AbstractPurpose of ReviewSystemic absorption of corticosteroids occurs following epidural administration. Central steroid response, including sleeplessness, flushing, and non-positional headache, insomnia, hiccups, flushing, and increased radicular pain, represents some of the most common immediate or delayed adverse event related to epidural steroid injections (ESI).Recent FindingsThe systemic effects of corticosteroids themselves likely represent the most commonly encountered complications that result from ESI. These include hyperglycemia, hypothalamic-pituitary-adrenal axis suppression, decreased bone mineral density, and others.SummaryThis narrative review is an up-to-date summary of the literature related to adverse events following ESI which are attributable to the systemic effects of corticosteroids.
Source: Current Physical Medicine and Rehabilitation Reports - Category: Rehabilitation Source Type: research

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In conclusion, the ISQ has appropriate face, content, and construct validity and is a reliable, stable and valid method to assess the past 12 month’s perceived immune status.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Relevance: Genetics of widespread human diseases is a branch of research which is actively developing. The study of polymorphisms of known candidate genes and their prognostic impact on the disease, is one of the important tasks in the study of tuberculosis.Objective: To prevent the development of adverse reactions due to pharmacotherapy in multi-drug resistant tuberculosis considering deletion polymorphism of the genes in the detoxification system of glutathione-S-transferase xenobiotics.Subject: We have examined 100 patients with newly diagnosed multidrug-resistant uberculosis (MDR-TB).Methods: Polymorphism GSTM1 and GST...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Tuberculosis Source Type: research
Introduction: Patients on chronic noninvasive ventilation must adapt to NIV. Little is known how side effects and associated symptoms influence adherence to NIV.Methods: Consecutive patients at outpatient NIV clinic were included, with underlying diseases: obesity hypoventilation syndrome (OHS), kyphoscoliosis (KS) and COPD. Side effects and associated symptoms on NIV were recorded systematically with a questionnaire.Results: 231 patients (47% OHS, 9% KS, 44% COPD) were included, 66% men, age 64 ± 12 years. Of these, 85% were adherent to NIV, with no difference between disease groups. Patients reported nocturia (62%...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Noninvasive ventilatory support Source Type: research
Rebound headaches, also known as medication overuse headaches, are caused by the frequent or excessive use of pain-relieving and/or antimigraine drugs to treat headache attacks that are already in progress. (Note that these are not the same as oral prophylactic or preventive medicines, which should be taken daily.) In other words, the same medications that initially relieve headache pain can themselves trigger subsequent headaches if they are used too often. Medication overuse headaches can be disabling, forcing people with this condition to take sick leave and to be less productive at work and home. To be diagnosed with m...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Drugs and Supplements Headache Health Source Type: blogs
The investigational Nocira device for acute migraine treatment non-invasively creates precisely controlled patterns of gentle air pressure changes in the outer ear. This stimulates unique pressure-activated nerve receptors, found only in the ear, that Nocira’s researchers hypothesize target and reset pain centers in the brain. Nocira presented its clinical pilot study data in September at the International Headache Congress in Dublin, showing that 20 out of 30 subjects were completely pain free, and 28 out of 30 had at least 50% relief, after just a 20-minute treatment with the device. “...
Source: MDDI - Category: Medical Devices Authors: Tags: Digital Health Source Type: news
Authors: Andrijauskis D, Ciauskaite J, Vaitkus A, Pajediene E Abstract AIMS: To evaluate the possible relationship between sleep disturbances and primary headaches. METHODS: This prospective study was carried out in a random group of patients with active primary headaches (case group) and a control group. Patients with active primary headaches were further stratified into two groups: patients with migraine and patients with tension-type headache (TTH). Participants were questioned using the following standardized tests: Insomnia Severity Index (ISI), Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Sca...
Source: Journal of Orofacial Pain - Category: ENT & OMF Tags: J Oral Facial Pain Headache Source Type: research
You're reading A Physician Letter Essay Sample, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles. From: Dr. Abu Salim Idris (Consultant Neurologist at KPJ Tawakkal Hospital/ MMC NO 23250 / nsr 124687/) To: Whom it may concern I Am writing regarding the health of my patient, name: MOHAMED YAHYA RASHEED AL JUMA, Passport NO: VP3153200 (OMAN), D.O.B: 01/07/1991 The above-mentioned patient was born on the 1st day of July 1991 in Oman and a student at the KDU University in Malaysia. The student is set to go back for hi...
Source: PickTheBrain | Motivation and Self Improvement - Category: Consumer Health News Authors: Tags: Uncategorized Source Type: blogs
The UK market for cannabidiol, a compound found in cannabis, will soon be worth £1bn. But consumers are being connedRoll up, roll up, ladies and gentleman, and gather around. Do you, your loved one – or family pet – suffer from any of the following conditions? Cancer, epilepsy, diabetes, arthritis, anxiety, menstrual cramps, insomnia, dry skin, psychosis, Alzheimer’s, dementia, anger, depression, ADHD, Crohn’s and IBS, PTSD, opiate addiction, Parkinson’s, pain of any kind, migraine, or canine uptightness? Then it’s your lucky day.Related:CBD: a marijuana miracle or just another hea...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Cannabis Drugs Society Health Medicine Science Pharmaceuticals industry Business Source Type: news
“Once you learn the art of relaxation, everything happens spontaneously and effortlessly.” – Amma During hectic times, it’s tough to remember that relaxation is more than a luxury. In fact, humans need to relax to maintain balance in their lives. Work stress, family strife, and mounting responsibilities can exact a tremendous toll. Relaxing should be at the top of the list as a healthy coping measure and as a rewarding self-gift. Why do we so often neglect this healing self-care? Do you know the healthiest ways to relax your mind, body and soul? Perhaps the biggest obstacle to relaxing is that some ...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Mental Health and Wellness Mindfulness Self-Help Source Type: blogs
Rui Yan1, ShiWan Tao1, HaiYan Liu1, Yu Chen1, JiaBo Shi1, YuYin Yang1, RongXin Zhu1, ZhiJian Yao1,2* and Qing Lu3,4*1Department of Psychiatry, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China2Nanjing Brain Hospital, Medical School of Nanjing University, Nanjing, China3School of Biological Sciences and Medical Engineering, Southeast University, Nanjing, China4Child Development and Learning Science, Key Laboratory of Ministry of Education, Nanjing, ChinaBackground: Major depressive disorders often involve somatic symptoms and have been found to have fundamental differences from non-somatic depressi...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
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