Where the Nurse Prescribes Heroin

A new program in Glasgow will give drug users pharmaceutical-grade heroin twice daily in a bid to reduce drug-related deaths.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Drug Abuse and Traffic Heroin Deaths (Fatalities) Acquired Immune Deficiency Syndrome Glasgow (Scotland) Great Britain Source Type: news

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Publication date: Available online 4 December 2019Source: International Journal for Parasitology: Parasites and WildlifeAuthor(s): Brenda Solórzano-García, Andrés Link Ospina, Silvia Rondón, Gerardo Pérez-Ponce de LeónAbstractPinworms of primates are believed to be highly host specific parasites, forming co-evolutionary associations with their hosts. In order to assess the strength and reach of such evolutionary links, we need to have a broad understanding of the pinworm diversity associated with primates. Here, we employed an integrative taxonomic approach to assess pinworm divers...
Source: International Journal for Parasitology: Parasites and Wildlife - Category: Parasitology Source Type: research
Publication date: January 2020Source: Antiviral Research, Volume 173Author(s): Yue Ma-Lauer, Yu Zheng, Miroslav Malešević, Brigitte von Brunn, Gunter Fischer, Albrecht von BrunnAbstractThe well-known immunosuppressive drug cyclosporin A inhibits replication of various viruses including coronaviruses by binding to cellular cyclophilins thus inactivating their cis-trans peptidyl-prolyl isomerase function. Viral nucleocapsid proteins are inevitable for genome encapsidation and replication. Here we demonstrate the interaction between the N protein of HCoV-229E and cyclophilin A, not cyclophilin B. Cyclophilin inhibitor...
Source: Antiviral Therapy - Category: Virology Source Type: research
Future Virology, Ahead of Print.
Source: Future Virology - Category: Virology Authors: Source Type: research
Publication date: Available online 5 December 2019Source: Genomics, Proteomics &BioinformaticsAuthor(s): Le Wang, Yan Xia, Yu Chen, Rujia Dai, Wenying Qiu, Qingtuan Meng, Liz Kuney, Chao ChenAbstractNeuropsychiatric disorders affect hundreds of millions of patients and families worldwide. To decode the molecular framework of these diseases, many studies use human postmortem brain samples. These studies reveal brain-specific genetic and epigenetic patterns via high-throughput sequencing technologies. Identifying best practices for the collection of postmortem brain samples, analyzing such large amounts of sequencing dat...
Source: Genomics, Proteomics and Bioinformatics - Category: Bioinformatics Source Type: research
Publication date: Available online 5 December 2019Source: Genomics, Proteomics &BioinformaticsAuthor(s): Yadong Yang, Yang Sui, Bingbing Xie, Hongzhu Qu, Xiangdong FangAbstractGliomas are one of the most common types of brain cancers. Numerous efforts have been devoted to studying the mechanisms of glioma genesis and identifying biomarkers for diagnosis and treatment. To help further investigations, we present a comprehensive database named GliomaDB. GliomaDB includes 21,439 samples from 4304 patients and integrates genomic, transcriptomic, epigenomic, clinical, and gene-drug association data regarding glioblastoma mul...
Source: Genomics, Proteomics and Bioinformatics - Category: Bioinformatics Source Type: research
Publication date: January 2020Source: Artificial Intelligence in Medicine, Volume 102Author(s): Wenping Tang, Aiqun Wang, S. Ramkumar, Radeep Krishna Radhakrishnan NairAbstractParalyzed patients were increasing day by day. Some of the neurodegenerative diseases like amyotrophic lateral sclerosis, Brainstem Leison, Stupor and Muscular dystrophy affect the muscle movements in the body. The affected persons were unable to migrate. To overcome from their problem they need some assistive technology with the help of bio signals. Electrooculogram (EOG) based Human Computer Interaction (HCI) is one of the technique used in recent ...
Source: Artificial Intelligence in Medicine - Category: Bioinformatics Source Type: research
Publication date: Available online 5 December 2019Source: Artificial Intelligence in MedicineAuthor(s): Zina Ben Miled, Kyle Haas, Christopher M. Black, Rezaul Karim Khandker, Vasu Chandrasekaran, Richard Lipton, Malaz A. BoustaniAbstractOur aim is to develop a machine learning (ML) model that can predict dementia in a general patient population from multiple health care institutions one year and three years prior to the onset of the disease without any additional monitoring or screening. The purpose of the model is to automate the cost-effective, non-invasive, digital pre-screening of patients at risk for dementia.Towards...
Source: Artificial Intelligence in Medicine - Category: Bioinformatics Source Type: research
Publication date: Available online 5 December 2019Source: Advances in Space ResearchAuthor(s): Lorenzo Niccolai, Alessandro Anderlini, Giovanni Mengali, Alessandro A. QuartaAbstractThe heliocentric orbital dynamics of a spacecraft propelled by a solar sail is affected by some uncertainty sources, including possible inaccuracies in the measurement of the sail film optical properties. Moreover, the solar radiation pressure, which is responsible for the solar sail propulsive acceleration generation, is not time-constant and is subject to fluctuations that are basically unpredictable and superimposed to the well-known 11-year ...
Source: Advances in Space Research - Category: Science Source Type: research
Publication date: Available online 5 December 2019Source: Advances in Space ResearchAuthor(s): Alessia De Iuliis, Francesco Ciampa, Leonard Felicetti, Matteo CeriottiAbstractLiterature on solar sailing has thus far mostly considered solar radiation pressure (SRP) as the only contribution to sail force. However, considering a sail in a planetary mission scenario, a new contribution can be added. Since the planet itself emits radiation, this generates a radial planetary radiation pressure (PRP) that is also exerted on the sail. Hence, this work studies the combined effects of both SRP and PRP on a sail for two case studies, ...
Source: Advances in Space Research - Category: Science Source Type: research
Publication date: Available online 5 December 2019Source: Advances in Space ResearchAuthor(s): Sergei I. Badulin, Vika G. Grigorieva, Pavel A. Shabanov, Vitali D. Sharmar, Ilya O. KarpovAbstractThe theory of similarity for wind-driven seas is applied to the physical analysis of the problem of sea state bias (SSB) in altimetry measurements. Dimensionless wave steepness and pseudo-age derived from altimetry measurements are expected to provide physically relevant and accurate enough SSB estimates. Analysis of Jason-1,2,3 and SARAL/AltiKa data within the approach shows the similarity and robustness of SSB distributions re-cas...
Source: Advances in Space Research - Category: Science Source Type: research
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