Meningococcal disease and vaccines: still many questions and some answers.
[Meningococcal disease and vaccines: still many questions and some answers]. Gac Sanit. 2019 Nov 22;: Authors: Godoy P, Castilla J, Astray J, Tuells J, Barrabeig I, Domínguez À PMID: 31767200 [PubMed - as supplied by publisher]
MenB vaccination programme has reduced cases of meningitis and septicaemia in young children by almost two-thirds.
New England Journal of Medicine,Volume 382, Issue 4, Page 309-317, January 2020.
New England Journal of Medicine,Volume 382, Issue 4, Page 318-327, January 2020.
Condition: Meningococcal Infections Intervention: Biological: Meningococcal Group ACYW135 Conjugate Vaccine Sponsor: Walvax Biotechnology Co., Ltd. Completed
Abstract Schools are increasingly being used to deliver vaccines. In 2015/16 three school-based vaccination programmes were delivered to adolescents in England: human papillomavirus (HPV), meningococcal groups A, C, W and Y disease (MenACWY) and tetanus, diphtheria and polio (Td/IPV). We assessed how school delivery models impact vaccine coverage and how a delivery model for one programme may impact another. Routinely collected national data were analysed to ascertain the school grade achieving highest coverage within each one-dose programme and to compare two-dose delivery models (within year vs across years) for...
In conclusion, Polish MenB (2010-2016) was highly diverse according to MLST and gene alleles encoding 4CMenB vaccine antigens. Some correlations between clonal complexes and variants of examined proteins/BAST profiles were revealed and a high coverage of 4CMenB vaccine was estimated. PMID: 31980191 [PubMed - as supplied by publisher]
Opisthotonos, extreme involuntary neck and back extension, is rarely seen in modern emergency departments. Vaccines have prevented the most common causes of this clinical presentation. Alternatively, otitis media is one of the most common pediatric infections and is characteristically non-invasive and harmless. In exceedingly rare cases, otitis media can develop complications and progress to invasive pneumococcal diseases including mastoiditis and meningitis. Streptococcus pneumoniae accounts for the majority of otitis media infections, however, since the introduction of the 7-valent pneumococcal conjugate vaccine (PCV7) a...