Drug-resistant staph spreads easily in households

(Reuters Health) - The superbug MRSA (methicillin-resistant Staphylococcus aureus) can spread easily from people to household pets, according to a new study that underscores the importance of frequent handwashing.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

Related Links:

ecka Milewski The development and spread of resistance of human pathogenic bacteria to the action of commonly used antibacterial drugs is one of the key problems in modern medicine. One of the especially dangerous and easily developing antibiotic resistant bacterial species is Staphylococcus aureus. Anthra[1,2-d][1,2,3]triazine-4,7,12(3H)-triones 22–38 have been developed as novel effective antistaphylococcal agents. These compounds have been obtained by sequential conversion of 1-amino-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid (1) and 1-amino-4-bromo-9,10-dioxo-9,10-dihydroanthracene-2-carboxyli...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Researchers from Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, and Nanyang Technological University (NTU) have designed an antimicrobial polymer that can kill bacteria resistant to commonly used antibiotics, including the superbug Methicillin-resistant Staphylococcus aureus (MRSA).
Source: World Pharma News - Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news
Conclusions: S. aureus SAgs belonging to the EGC are highly prevalent in CF clinical isolates. The greater prevalence in these SAgs in CF airway specimens compared to skin isolates suggests that these toxins confer selective advantage in the CF airway.
Source: Genes - Category: Genetics & Stem Cells Authors: Tags: Article Source Type: research
Foods may potentially serve as vehicles for the transmission of antimicrobial-resistant variants of Staphylococcus aureus that are important in a human clinical context. Further, retail food products can be a cause of staphylococcal food poisoning. For these reasons and to account for source attribution and risk assessment, detailed information on the population structure, resistance, and virulence profiles of S. aureus originating from retail food products is necessary. In the current study, whole-genome sequences from 88 S. aureus isolates were subjected to bioinformatics analyses in relation to sequence types, antimicro...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
CONCLUSION: Our data showed the potential of this series for exploring new and more effective antibacterial in order to develop in vivo and against other resistant bacteria. PMID: 31820692 [PubMed - as supplied by publisher]
Source: Current Topics in Medicinal Chemistry - Category: Chemistry Authors: Tags: Curr Top Med Chem Source Type: research
AbstractThe aim of this study was to evaluate the diagnostic accuracy and the clinical impact of isothermal loop-mediated amplification (LAMP; eazyplex ® MRSA kits) for rapid diagnosis ofStaphylococcus aureus bacteremia (SAB) in comparison with conventional blood culture diagnostics. We performed a retrospective, single-center observational study over the period between November 2016 and December 2018 on patients (and blood cultures) with growth of Gram-positive cocci in clusters in their blood cultures. We quantified diagnostic accuracy with sensitivity and specificity for detection ofS. aureus, methicillin-resistantS...
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research
Publication date: Available online 9 December 2019Source: International Journal of PharmaceuticsAuthor(s): Mohammed Salih, Calvin A. Omolo, Nikhil Agrawal, Pavan Walvekar, Ayman Y. Waddad, Chunderika Mocktar, Charlotte Ramdhin, Thirumala GovenderAbstractThe global threat of antimicrobial resistant strains calls for innovative strategies to utilize nano drug delivery systems to enhance the delivery of antibiotics, thus reducing the development of resistance. Supramolecular amphiphiles that can self-assemble into nanostructures are one such nano delivery system, that are showing potential for effective drug delivery. The aim...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
Abstract A phase 2 study of gepotidacin demonstrated the safety and efficacy of 3 gepotidacin doses (750 mg every 12h [q12h], 1,000 mg q12h, and 1,000 mg every 8h [q8h]) in hospitalized patients with suspected/confirmed Gram-positive acute bacterial skin and skin structure infections (ABSSSIs). Evaluating microbiology outcomes and responses were secondary endpoints. Pretreatment isolates recovered from infected lesions underwent susceptibility testing per Clinical and Laboratory Standards Institute guidelines. Staphylococcus aureus accounted for 78/102 (76%) Gram-positive isolates; 54/78 (69%) were methicillin-res...
Source: Antimicrobial Agents and Chemotherapy - Category: Microbiology Authors: Tags: Antimicrob Agents Chemother Source Type: research
Publication date: Available online 3 December 2019Source: Journal of Photochemistry and Photobiology B: BiologyAuthor(s): Kandasamy Saravanakumar, Elango Jeevithan, Xiaowen Hu, Ramachandran Chelliah, Deog-Hwan Oh, Myeong-Hyeon WangAbstractThis work reports the optimization, synthesis, characterization, anticancer, and antibacterial activity of the Trichoderma-β-D-glucan‑zinc oxide nanoparticles (T-β-D-glu-ZnO NPs). Firstly, the T-ZnO NPs was synthesized using the fungal mycellial water extract (FWME) derived from T. harzianum strain SKCGW009 under the optimized condition of extract concentration (5.99 mL), te...
Source: Journal of Photochemistry and Photobiology B: Biology - Category: Speech-Language Pathology Source Type: research
Staphylococcus aureus is one of the major causes of nosocomial infections. This organism produces powerful toxins and cause superficial lesions, systemic infections, and several toxemic syndromes. A total of 109 S. aureus strains isolated from a variety of infections like ocular diseases, wound infection, and sputum were included in the study. Minimum inhibitory concentration (MIC) was determined against 8 antimicrobials. PCR determined the presence of 16S rRNA, nuc, mecA, czrC, qacA/B, pvl, and toxin genes in S. aureus isolates. Pulse-field gel electrophoresis (PFGE), multi-locus sequence typing (MLST), SCCmec, spa-, and ...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
More News: Health | Infectious Diseases | MRSA | Staphylococcus Aureus | Study | Superbugs