Could hibernation treat obesity? Obese people share similar genes with hibernating animals

The discovery, reported today in a new study by the University of Utah, could shed light on the root causes of metabolic disorders and ways to treat, or even cure, them.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Journal Name: Clinical Chemistry and Laboratory Medicine (CCLM) Issue: Ahead of print
Source: Clinical Chemistry and Laboratory Medicine - Category: Laboratory Medicine Source Type: research
Authors: Fogato L Abstract Will I actually be ready to face my first surgical on call night? It is the question that haunts every young specialist when, once he has completed his surgical training, he is alone, often by night to face the unpredictable. It is a question of ethical and intellectual honesty to understand that learning curve is something quite different from being transformed from a surgeon by day into a superhero by night. The training gap in Italy and at the same time the typology of patients (obesity, age, gunshot wounds, and stab wounds) who come to our Emergency Departments have exasperated the ne...
Source: Annali Italiani di Chirurgia - Category: Surgery Tags: Ann Ital Chir Source Type: research
Publication date: Available online 10 December 2019Source: American Journal of Preventive MedicineAuthor(s): Wudeneh M. MulugetaIntroductionLittle is known about the longitudinal trends and factors associated with obesity and overweight among U.S. immigrants and ethnic minorities.MethodsAt a large safety net health system in Massachusetts, 7,973 adults were followed retrospectively for 42.0 months on average from 2011 to 2016. Multivariate analyses were performed to identify factors associated with obesity (BMI ≥30 kg/m2) and overweight (BMI ≥25 kg/m2). Data were collected and analyzed in 2018–2019.ResultsObesi...
Source: American Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
ConclusionsAn inverse correlation between TL and obesity traits was observed in children with abdominal obesity. Interestingly, we found that baseline TL could predict changes in blood glucose levels.Clinical TrialNCT03147261. Registered 10 May 2017.
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
Saying how far consumers need to walk to burn off the calories could change eating habitsLabelling food and drinks with how much walking or running is needed to burn them off could help tackle the obesity crisis, researchers say.While all packaged food must display certain nutritional information, such as calorie content,there is limited evidence that the approach changes what people buy or eat. Meanwhile,waistlines continue to expand.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Obesity Food Health Society UK news Science Nutrition Source Type: news
ConclusionsSeveral risk factors may play a role in evolution of MS. Our results show that smoking status, probably due to chronic vascular and neurotoxic effects of the cigarette components, can affect the brain damage from the early stages of MS. No association was observed with the other explored modifiable risk factors, although an effect due to the small sample size cannot be excluded.
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Conclusions: These findings suggest that HON can prevent diet-induced obesity and its associated diseases by regulating the gut microbiota and improving microbial metabolite levels. Moreover, our findings indicate that sex may be an important factor affecting HON activity.
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Macrophages are heterogeneous leukocytes regulated in a tissue- and disease-specific context. While in vitro macrophage models have been used to study diseases empirically, a systematic analysis of the transcriptome thereof is lacking. Here, we acquired gene expression data from eight commonly-used in vitro macrophage models to perform a meta-analysis. Specifically, we obtained gene expression data from unstimulated macrophages (M0) and macrophages stimulated with lipopolysaccharides (LPS) for 2–4 h (M-LPSearly), LPS for 24 h (M-LPSlate), LPS and interferon-γ (M-LPS+IFNγ), IFNγ (M-IFNγ), inter...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Only half of patients dealing with infertility issues in the UK receive psychological support Related items fromOnMedica Strong women ’s rights linked to better health Women should have access to one stop health clinics Tackling obesity ‘must be made a national priority’ Biological clock predictor could help mothers-to-be Smoking linked to earlier menopause
Source: OnMedica Latest News - Category: UK Health Source Type: news
Overweight and obese children tend to have a thinner prefrontal cortex, a part of the brain associated with decision-making and problem-solving.
Source: WebMD Health - Category: Consumer Health News Source Type: news
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