Gastric Bypass Beats Sleeve Gastrectomy for Diabetes Remission Gastric Bypass Beats Sleeve Gastrectomy for Diabetes Remission

Among obese patients with type 2 diabetes, gastric bypass is associated with higher rates of diabetes remission at one year than is sleeve gastrectomy, researchers from Norway report.Reuters Health Information
Source: Medscape General Surgery Headlines - Category: Surgery Tags: Diabetes & Endocrinology News Source Type: news

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As recently summarized1, there are only four randomized clinical trials (RCTs) in patients with type 2 diabetes mellitus (T2DM) comparing Roux-en-Y gastric bypass (RYGB) with sleeve gastrectomy (SG) and providing level I evidence up to 5 years after randomization.2-5 None of the individual studies were primarily designed and adequately powered to compare the effects of RYGB with SG on T2DM. However, combined analysis of these RCTs (i.e. meta-analysis) in order to increase the sample size and statistical power (RYGB, n=176 versus SG, n=175) would indicate that either there is no significant long-term difference between RYGB...
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Letter to the Editor Source Type: research
This study included patients who underwent primary laparoscopic Roux-en-Y gastric bypass (LRYGB) or laparoscopic sleeve gastrectomy (LSG). The primary outcome of interest was incisional SSI occurring within 30  days. Surgeries performed in 2015 were used in a derivation cohort and the predictive tool was validated against the 2016 cohort. A forward selection algorithm was used to build a logistic regression model predicting probability of SSI.ResultsA total of 274,187 patients were included with 71.7% being LSG and 28.3% LRYGB. 0.7% of patients had a SSI in which 71.0% had an incisional SSI, and 29.9% had an organ/spa...
Source: Surgical Endoscopy - Category: Surgery Source Type: research
Objective: We sought to compare the short and long-term outcomes of MBS in adolescents vs. adults who have undergone a Roux-en-Y gastric bypass (RYGB) or Sleeve gastrectomy (SG).Design: Retrospective cohort study.Setting: Single tertiary care academic referral center.Participants: One hundred fifty adolescent (≤ 21-years) and adult (>21-years) subjects with severe obesity between 15 and 70 years of age who underwent RYGB or SG.Outcomes: Metabolic parameters, weight and height measures were obtained pre-and post-surgery (at 3 and 6 months, and then annually for 4 years).Results: Median pre-surgical body mass index (BM...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
AbstractBackgroundRevisional gastric bypass (R-RYGB) surgery is utilized for the management of inadequate weight loss or weight regain observed after some cases of bariatric surgeries. Data on the mid-term effectiveness of primary gastric bypass (P-RYGB) compared with R-RYGB (e.g., post sleeve gastrectomy/gastric banding) are controversial.MethodsRetrospective chart review of all patients who received P-RYGB and R-RYGB (January 2011 –June 2015) at our center. One hundred twenty patients who underwent P-RYGB and 34 R-RYGB who completed 18 months follow-up were included. We compared the effectiveness of P-RYGB with R-R...
Source: Obesity Surgery - Category: Surgery Source Type: research
In patients with both severe obesity and diabetes, bariatric surgery can often improve diabetes, and in some, gastric bypass is even more effective than sleeve gastrectomy, a study has found.Medscape Medical News
Source: Medscape General Surgery Headlines - Category: Surgery Tags: Diabetes & Endocrinology News Source Type: news
Type 2 diabetes (T2DM) is closely associated with obesity. Given that weight loss is associated with T2DM remission, there has been intense interest in diabetes outcomes following bariatric surgery. The landmark Surgical Therapy and Medications Potentially Eradicate Diabetes Efficiently (STAMPEDE) trial found that bariatric surgery was a more effective diabetes treatment compared with medical management after 5 years of follow-up. While it was not adequately powered to detect differences between Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG), other randomized clinical trials have found no differences in diabet...
Source: JAMA Surgery - Category: Sports Medicine Source Type: research
ConclusionsMild-to-moderate PPHG is a frequent complication after bariatric surgery and results in smaller weight loss after 2  years. Age, baseline BMI, and an earlier glucose peak during OGTT predict PPHG after bariatric surgery.
Source: Obesity Surgery - Category: Surgery Source Type: research
CONCLUSION: This study reports similar T2DM resolution rates by both LRYGB and LSG during 1-5 years of follow-up. However, long-term follow-up of 10 years is needed to further substantiate these findings. PMID: 32148383 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Tags: World J Gastroenterol Source Type: research
Authors: Koch TR, Shope TR Abstract Obesity is a major factor in the worldwide rise in the prevalence of type 2 diabetes mellitus. The obesity "epidemic" will require novel, effective interventions to permit both the prevention and treatment of diabetes caused by obesity. Laparoscopic vertical sleeve gastrectomy is a newer bariatric surgical procedure with a lower risk of complications (compared to Roux-en-Y gastric bypass surgery). Based in part on restriction of daily caloric intake, sleeve gastrectomy has a major role in inducing significant weight loss and weight loss is maintained for at least 10&nbs...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Conclusion: Candidates for bariatric/metabolic surgery favored SG followed by AGB, GP, and RYGB, and their choices were compatible with current evidence-based clinical practice. PMID: 32051816 [PubMed]
Source: Annals of Surgical Treatment and Research - Category: Surgery Tags: Ann Surg Treat Res Source Type: research
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