Parkinson's tremors could be treated with SOUNDWAVES, claim scientists

Researchers from the University of L'Aquila in Italy looked at 39 patients whose shakes had not been curbed by drugs. They found 95% saw their symptoms immediately reduced after treatment.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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DiscussionThese findings provide evidence supporting the use of technology-driven interventions aiming at alleviating rhythm-related motor deficits in PD such as hypokinetic dysarthria or gait impairment in complement to more traditional therapeutic approaches.
Source: Neurophysiologie Clinique - Category: Neuroscience Source Type: research
ConclusionsOur results showed that VADL and ABC questionnaires, applied before and after rehabilitation, were important tools to measure the independence, confidence and balance while developing daily activities. VADL and ABC questionnaires may effectively contribute to quantify the effect of the applied therapeutics and, consequently, its impact on the quality of life of patients with PD.
Source: Neurophysiologie Clinique - Category: Neuroscience Source Type: research
ConclusionsStimulation of STN at 80 Hz and 130 Hz may have different effects on proximal and distal muscle control. One hundred and thirty Hertz may have a small advantage for distal hand muscles, whereas 80 Hz is more effective in improving proximal muscle function.
Source: Neurophysiologie Clinique - Category: Neuroscience Source Type: research
Discussion/conclusionCette étude suggère que la SCP de la RLM ne permet pas d’améliorer significativement les capacités locomotrices et le contrôle postural des patients avec maladie de Parkinson évoluée. Une meilleure compréhension des mécanismes neuronaux impliquant cette région cérébrale dans la survenue de ces troubles reste nécessaire à l’élaboration de nouvelles stratégies thérapeutiques.
Source: Neurophysiologie Clinique - Category: Neuroscience Source Type: research
ConclusionLes tâches de résolution de conflit entraînent une altération de l’initiation du pas similaire chez les freezers, non-freezers et témoins. L’électroencéphalographie durant l’ANT combiné à l’initiation du pas semble être pertinente pour une meilleure compréhension de l’influence de l’attention sur l’initiation du pas dans la maladie de Parkinson.
Source: Neurophysiologie Clinique - Category: Neuroscience Source Type: research
Discussion/conclusionFallers distinguished from non-fallers by disease duration and motor impairment but adding gait measurement improves the accuracy of the clinical data. Further research should concentrate to validate these models in prospective cohorts.
Source: Neurophysiologie Clinique - Category: Neuroscience Source Type: research
Discussion/conclusionCes données préliminaires sont en accord avec l’hypothèse de processus d’inhibition proactive, précédant l’initiation du pas, impliquant potentiellement le NST dans la levée de l’inhibition motrice.
Source: Neurophysiologie Clinique - Category: Neuroscience Source Type: research
Discussion/conclusionLes données préliminaires de cette étude clinique en cours suggèrent que ce programme de rééducation par le jeu vidéo « Toap Run » permet une amélioration du temps de marche chez les patients avec MPI.
Source: Neurophysiologie Clinique - Category: Neuroscience Source Type: research
Publication date: Available online 6 December 2019Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Eun-Jin Bae, Seung-Jae LeeAbstractLRRK2 and SNCA, the gene for α-synuclein, are the two of the most important genetic factors of Parkinson's disease (PD). A-synuclein is aggregated and accumulated in neurons and glia in PD and considered the pathogenic culprit of the disease. A-synuclein aggregates spread from a few discrete regions of the brain to larger areas as the disease progresses through cell-to-cell propagation mechanism. LRRK2 is involved in the regulation of vesicle traffickin...
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - Category: Molecular Biology Source Type: research
Condition:   Parkinson Disease Intervention:   Sponsor:   Gazi University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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