Imaging Features of Urachal Cancer: A Case Report

We present a case of a 45-year-old male patient presenting with painless hematuria of 1 week's duration and display the US and CT images. Imaging shows: (1) a solid, ill-defined, irregularly shaped mass invading the bladder wall located between the dome of the bladder and the abdominal wall, and which underwent significant enhancement; (2) hypo-echoic, heterogeneous echopattern with some calcifications and (3) patchy and short-line blood flow signals within the mass. Final histopathology confirmed urachal adenocarcinoma.
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research

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We report a urachal adenocarcinoma case managed surgically with two incisions and an emphasis on cosmesis while maintaining oncologic principles.
Source: Urology - Category: Urology & Nephrology Authors: Tags: Surgical Techniques in Urology Source Type: research
AbstractPurposeTo test the effect of tumor location (urachal vs. non-urachal) on cancer-specific mortality (CSM) in patients with adenocarcinoma of the urinary bladder (ADKUB).Materials and methodsWithin the Surveillance, Epidemiology, and End Results registry (2004 –2016), we identified patients with non-metastatic (≤ T4N0M0) ADKUB. Stratification was made according to tumor location: urachal vs. non-urachal ADKUB. Kaplan–Meier plots and multivariable Cox regression models were fitted before and after 1:3 propensity score (PS) matching and separate Cox r egression models were refitted before and after inver...
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research
Abstract Urachal carcinoma is a highly uncommon malignancy with an estimated prevalence of 0.01% to 0.02% of all adult cancers. Due to its rarity, no standardized management protocol for urachal cancer has been developed. Surgery is often the main therapeutic measure. A 48-year-old man presented with hematuria for 8 months. Imaging revealed a mass at the bladder dome. Biopsy indicated mixed adenocarcinoma with a small cell component. Radical cystoprostatectomy with ileal urostomy was performed. After surgical resection, he was diagnosed with urachal adenocarcinoma (mixed type). The patient tolerated surgery and wa...
Source: Baylor University Medical Center Proceedings - Category: Universities & Medical Training Authors: Tags: Proc (Bayl Univ Med Cent) Source Type: research
CONCLUSION: NUBTs present with similar clinicoradiological findings; however, their histological features along with immunohistochemistry help in the definite diagnosis. One should be aware of these tumors as they frequently present diagnostic and therapeutic challenge. Most of these neoplasms present at an advanced stage. Large or multicentric randomized controlled studies are needed to know the exact behavior and prognosis of these tumors.
Source: Indian Journal of Cancer - Category: Cancer & Oncology Authors: Source Type: research
Publication date: Available online 31 May 2019Source: Cancer GeneticsAuthor(s): Amit Sharma, Holger Fröhlich, Rong Zhang, Anne-Karoline Ebert, Wolfgang Rösch, Henning Reis, Glen Kristiansen, Jörg Ellinger, Heiko ReutterAbstractThe bladder exstrophy-epispadias complex (BEEC) represents the severe end of uro-rectal malformation spectrum involving aberrant embryonic morphogenesis of the cloacal membrane and the urorectal septum. The most common form of BEEC is isolated classic bladder exstrophy (CBE). Long-term complications in CBE are malignancies of the bladder with 95% of them being adenocarcinomas. Since CB...
Source: Cancer Genetics - Category: Cancer & Oncology Source Type: research
CONCLUSION: mpMRI of the prostate may yield incidental findings, such as small bladder tumors. Awareness of the possibility of incidental bladder lesions is important as 65% of lesions reported in the bladder, not attributable to extension of prostate cancer, proved to be bladder cancer. This may allow for early intervention for asymptomatic patients with undetected bladder cancer prior to disease progression. PMID: 30211685 [PubMed - in process]
Source: Diagnostic and Interventional Radiology : The Turkish Society of Radiology - Category: Radiology Authors: Tags: Diagn Interv Radiol Source Type: research
AbstractPurposeTo review the United States  National Cancer Database (NCDB) from 2004 to 2015 and analyze survival outcomes of invasive non-urachal adenocarcinoma based on treatment modality.MethodsThe NCDB 2004 –2015 bladder dataset was queried for adenocarcinoma histology, excluding urachal variant, and limited to patients with clinical stage T2–T4 disease. Treatment modality was categorized as no treatment, cystectomy (partial or radical), external beam radiation therapy (EBRT), or EBRT plus cystecto my. Our primary outcome was overall survival. Cox regression (CR) and Kaplan–Meier (KM) analysis w...
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research
Authors: Reis H, Krafft U, Niedworok C, Módos O, Herold T, Behrendt M, Al-Ahmadie H, Hadaschik B, Nyirady P, Szarvas T Abstract Urachal cancer (UrC) is a rare but aggressive cancer. Due to overlapping histomorphology, discrimination of urachal from primary bladder adenocarcinomas (PBAC) and adenocarcinomas secondarily involving the bladder (particularly colorectal adenocarcinomas, CRC) can be challenging. Therefore, we aimed to give an overview of helpful (immunohistochemical) biomarkers and clinicopathological factors in addition to survival analyses and included institutional data from 12 urachal adenocarc...
Source: Disease Markers - Category: Laboratory Medicine Tags: Dis Markers Source Type: research
CONCLUSION: Total mesenteric peritonectomy can be safely performed with the reported technique irrespective of how widespread PM is along the mesentery as long as few small bowel serous membranes are involved. PMID: 28986751 [PubMed - as supplied by publisher]
Source: Ann Oncol - Category: Cancer & Oncology Authors: Tags: Ann Surg Oncol Source Type: research
ConclusionTotal mesenteric peritonectomy can be safely performed with the reported technique irrespective of how widespread PM is along the mesentery as long as few small bowel serous membranes are involved.
Source: Annals of Surgical Oncology - Category: Cancer & Oncology Source Type: research
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