Combination of negative pressure wound therapy using vacuum-assisted closure and ozone water flushing for treatment of diabetic foot ulcers

ConclusionThe combination use could enhance the recovery of DFUs, shorten the treatment duration, and reduce the pain during treatment.
Source: International Journal of Diabetes in Developing Countries - Category: Endocrinology Source Type: research

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Source: Medgadget - Category: Medical Devices Authors: Tags: Critical Care Exclusive Medicine Plastic Surgery Vascular Surgery Source Type: blogs
​BY HABIR MANDAIR; KEYUR KURANI; &KHALID MALIK, MDA 62-year-old obese woman with end-stage renal disease (ESRD) who was on hemodialysis, hypertension, diabetes mellitus, and chronically elevated serum calcium levels presented to the ED with altered mental status. Nursing home staff stated that she was unable to answer questions coherently and seemed confused.Her vitals were within normal limits except for a body temperature of 99.9°F. Several necrotic lesions of various sizes were found on her left and right buttocks and the medial aspects of both thighs. The patient also had severe necrosis of the third finger o...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research
  How do you know if your wound is chronic? The severity of your injury, as well as complications that cause significant delays in healing, are common indicators. There are also certain kinds of wounds that often end up high on the chronic scale. Here are the three most common types of chronic wounds: Infectious wounds, surgical sites and ulcers are among the most common chronic wounds. 1. Infectious wounds When infection causes significant delays in healing, the wound often becomes chronic. According to Wound Care Centers, typical signs of chronic infectious wounds include bad odors, pus drainage, dead ti...
Source: Advanced Tissue - Category: Dermatology Authors: Tags: Wound Care Wound Infection chronic wounds Source Type: news
We report the application of a free vascularized medial femoral condyle flap to prevent the recurrence of pressure ulcer in a patient with diabetic foot syndrome. Our patient had type 2 diabetes and presented with pressure ulcers and osteomyelitis of metatarsal heads 2 and 3 after a great toe amputation. We chose to use a medial femoral condyle flap as a damper in the area of the metatarsal heads because of the relatively young age and good vascularity of our patient. We shaped the graft like a ski to distribute the pressure and prevent perforation of the plantar skin. Good results were achieved for wound healing, pain red...
Source: The Journal of Foot and Ankle Surgery - Category: Orthopaedics Source Type: research
Authors: Shu X, Shu S, Tang S, Yang L, Liu D, Li K, Dong Z, Ma Z, Zhu Z, Din J Abstract Diabetic foot ulcer is a chronic, refractory, frequent complication in diabetic patient. Its treatment often requires multidisciplinary joint efforts, diverse strategies have been adopted to address this annoying issue, including stem cell-based therapy/acellular dermal matrix/negative pressure wound therapy etc. However, consensus has not been reached. To assess the current evidence regarding the efficiency and potential advantages of stem cell-based therapy compared with conventional standard treatment and/or placebo in the tr...
Source: Endocrine Journal - Category: Endocrinology Tags: Endocr J Source Type: research
Authors: Pinto NR, Ubilla M, Zamora Y, Del Rio V, Dohan Ehrenfest DM, Quirynen M Abstract Chronic wounds (VLU: venous leg ulcer, DFU: diabetic foot ulcer, PU: pressure ulcer, or complex wounds) affect a significant proportion of the population. Despite appropriate standard wound care, such ulcers unfortunately may remain open for months or even years. The use of leukocyte- and platelet-rich fibrin (L-PRF) to cure skin ulcers is a simple and inexpensive method, widely used in some countries but unknown or neglected in most others. This auto-controlled prospective cohort study explored and quantified accurately for t...
Source: Platelets - Category: Hematology Tags: Platelets Source Type: research
ConclusionsThe present meta‐analysis shows that the evidence base for silver in wound management is significantly better than perceived in the current scientific debate. Thus, if used selectively and for a limited period of time, silver not only has antimicrobial effects but is also characterized by an improvement in quality of life and good cost‐effectiveness.
Source: JDDG - Category: Dermatology Authors: Tags: Original Article Source Type: research
CONCLUSIONS: Both drugs are efficacious. Tetrachlorodecaoxide yields healthy granulation tissue earlier. Both drugs appear to be safe for application. PMID: 27689045 [PubMed]
Source: Archives of Plastic Surgery - Category: Cosmetic Surgery Tags: Arch Plast Surg Source Type: research
This review presents a closer look at four diseases which are probably closely related to one another pathophysiologically: (a) calciphylaxis (distal pattern); (b) calciphylaxis (proximal pattern); (c) Martorell hypertensive ischemic leg ulcer; (d) calciphylaxis with normal renal and parathyroid function (synonym: eutrophication). The four diseases have largely the same risk factors: (1) arterial hypertension, (2) diabetes mellitus (types 1 and 2), (3) secondary or tertiary hyperparathyroidism (in end-stage kidney disease) and (4) oral anticoagulation with vitamin K antagonists. They share the same clinical patterns: necro...
Source: Dermatology - Category: Dermatology Source Type: research
It has been estimated that a limb is lost every 30s in the world due to diabetes. This trend is expected to be multiplied by four in the next 15 years with the pandemic evolution of diabetes [22]. In addition to causing pain and morbidity, foot lesions in diabetic patients have substantial direct and indirect economic consequences [23,9]. Diabetic foot ulcers result from multiple pathophysiological mechanisms, including neuropathy, peripheral vascular disease, high foot pressures, foot deformity, and diabetes severity [25].
Source: Medical Engineering and Physics - Category: Biomedical Engineering Authors: Source Type: research
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