Identifying molecularly defined antigens for a Histoplasma capsulatum-specific interferon gamma release assay.

CONCLUSIONS: The H. capsulatum genome encodes a large number of distinctive proteins, which represent a valuable source of potential specific antigens for an IGRA test. Among them, the Cfp4 protein stands out as a very attractive candidate.
PMID: 31757594 [PubMed - as supplied by publisher]

Source: Revista Iberoamericana de Micologia - November 18, 2019 Category: Biology Authors: Rubio-Carrasquilla M, Ochoa R, Santa C, Guimarães AJ, Cano LE, Moreno E Tags: Rev Iberoam Micol Source Type: research