Outcomes of Stenotrophomonas maltophilia hospital-acquired pneumonia in intensive care unit: a nationwide retrospective study

There is little descriptive data on Stenotrophomonas maltophilia hospital-acquired pneumonia (HAP) in critically ill patients. The optimal modalities of antimicrobial therapy remain to be determined. Our objectiv...
Source: Critical Care - Category: Intensive Care Authors: Tags: Research Source Type: research

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Little is known about risk and prognostic factors in very old patients developing sepsis secondary to community-acquired pneumonia (CAP). In very old patients hospitalized with CAP, in-hospital and 1-year mortality rates were increased if they developed sepsis. Antibiotic therapy before hospital admission was associated with a lower risk of sepsis.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
This case of a 7-year-old patient highlights the need to consider the diagnosis of Kawasaki disease in the presence of pneumonia and pleural effusion that is nonresponsive to antibiotic therapy.Journal of Medical Case Reports
Source: Medscape Critical Care Headlines - Category: Intensive Care Tags: Family Medicine/Primary Care Journal Article Source Type: news
CONCLUSION: S. aureus was the predominant causative agent of nosocomial pneumonia. The most frequent risk factor identified for infection with multidrug-resistant organisms was previous treatment with antibiotics. Multidrug-resistant organisms were present in 45% of documented hospital-acquired pneumonias. In admitted patients with non-intensive care unit acquired pneumonia, the intensive care unit mortality rate was nearly five times higher compared to intensive care unit acquired pneumonia. PMID: 31851883 [PubMed - in process]
Source: Acta Medica Portuguesa - Category: General Medicine Tags: Acta Med Port Source Type: research
CONCLUSION: Early C-reactive protein kinetics is not associated with response and prognostic assessment in infected critically ill patients. Nevertheless, a fast response pattern tends to exclude initial inappropriate antibiotic therapy. PMID: 31851882 [PubMed - in process]
Source: Acta Medica Portuguesa - Category: General Medicine Tags: Acta Med Port Source Type: research
The manufacturer of ceftolozane with tazobactam anticipates that it will be used in line with good antimicrobial stewardship, on the advice of a microbiologist, to treat critically ill ventilated adults with HAP and VAP, who are deteriorating or not responding to initial antibiotic therapy, and who have confirmed or highly suspected Pseudomonas aeruginosa. Specialists involved in producing this evidence summary consider that ceftolozane with tazobactam provides a potentially useful alternative for treating some adults with HAP and VAP who have limited treatment options because they have infections suspected or proven to be...
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
ConclusionsIn patients with AHF, a strategy of PCT ‐guided initiation of ABX was not more effective than a standard care strategy in improving clinical outcomes.
Source: European Journal of Heart Failure - Category: Cardiology Authors: Tags: Research Article Source Type: research
In conclusion, antibiotic therapy was often incomplete, was generally guideline discordant, exhibited limited diversity of selection, and frequently lacked diagnostic confirmation. These data, combined with local susceptibility patterns, may be used to foster AMS efforts for improved compliance with guidelines at MZRH in the future. PMID: 31802729 [PubMed - as supplied by publisher]
Source: Am J Trop Med Hyg - Category: Infectious Diseases Authors: Tags: Am J Trop Med Hyg Source Type: research
We hereby report a case of subclinical community ‐acquiredAcinetobacter pneumonia in association with a mature cystic teratoma masquerading as a lung abscess. A 22 ‐year‐old lady presented with fever and right pleuritic chest pain with chest X‐ray showing a right suprahilar shadow. Her symptoms largely subsided with antibiotic therapy but the shadow remained unresolved. Computerized tomography (CT) scan of thorax showed consolidation over the anterior se gment of the right upper lobe with a hypodense area suspicious of a lung abscess. Fine needle aspirates of the lesion grewAcinetobacter baumannii twice but the sha...
Source: Respirology Case Reports - Category: Respiratory Medicine Authors: Tags: Case Report Source Type: research
Rationale: Acute fibrinous and organizing pneumonia (AFOP) is a newly evolving rare non-infectious lung pathology, characterized by intra-alveolar fibrin balls on histology. It is usually difficult to be diagnosed and mistaken for other lung diseases. Patient concerns: In this article, an interesting case about a male patient with a 15-day history of high-grade fever, chills, and no productive cough was presented. He was misdiagnosed as the lung infection early, but exhibited no response to the antibiotic therapy. Diagnosis: The diagnosis of AFOP was determined by the lung biopsy and pathology. Interventions: Wi...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
This report describes a fatal S stercoralis hyperinfection in a patient with nephrotic syndrome after treatment with steroids. Patient concerns: A 70-year-old male presented with a history of progressive edema, skin infection, persistent fever, cough, intermittent abdominal pain, and progressive respiratory failure after steroid treatment. Diagnosis: Nephrotic syndrome; cellulitis; S stercoralis hyperinfection; Klebsiella pneumonia. Interventions: During the first hospital admission, the patient was administered full-dose glucocorticoid and antibiotic therapy after suffering from cellulitis. During the second admi...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
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