Disruption of crosstalk between LX-2 and liver cancer stem-like cells from MHCC97H cells by DFOG via inhibiting FOXM1.

This study demonstrated that DFOG disrupts the crosstalk between HSCs and LCSLCs to suppress LCSLC features via down-regulating FOXM1 expression and reducing HGF secretion in HSCs.
PMID: 31750892 [PubMed - as supplied by publisher]

Source: Acta Biochimica et Biophysica Sinica - November 20, 2019 Category: Biochemistry Authors: Chen A, Xu C, Luo Y, Liu L, Song K, Deng G, Yang M, Cao J, Yuan L, Li X Tags: Acta Biochim Biophys Sin (Shanghai) Source Type: research