AHA News: Areas Hit Hardest by Recession Saw Jump in Heart Death Rates

FRIDAY, Nov. 22, 2019 (American Heart Association News) -- Communities suffering the most after the Great Recession had the biggest increase in heart disease deaths in the years that followed, according to a new study. After decades of decline, the...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news

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This study delves into the mechanisms by which a short period of fasting can accelerate wound healing. Fasting triggers many of the same cellular stress responses, such as upregulated autophagy, as occur during the practice of calorie restriction. It isn't exactly the same, however, so it is always worth asking whether any specific biochemistry observed in either case does in fact occur in both situations. In particular, the period of refeeding following fasting appears to have beneficial effects that are distinct from those that occur while food is restricted. Multiple forms of therapeutic fasting have been repor...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Discussion: The above data should prompt neurologists, cardiologists and family doctors to try to detect AF as a risk factor for ischemic stroke which worsens patient prognosis, prolongs hospital stay and contributes to increase in mortality, especially when more effective drug treatment is currently possible. PMID: 32241245 [PubMed - as supplied by publisher]
Source: Neurological Research - Category: Neurology Tags: Neurol Res Source Type: research
Authors: Dahal S, Budoff MJ Abstract The results of the ISCHEMIA (International Study of Comparative Health Effectiveness With Medical and Invasive Approach) trial were presented at the American Heart Association Scientific Sessions in November, 2019 in Philadelphia, Pennsylvania, and recently published on March 30, 2020 in the New England Journal of Medicine. After an average follow-up of 3.5 years, invasive therapy did not reduce the major adverse cardiac event (MACE) rate compared with optimal medical therapy (OMT) in patients with stable ischemic heart disease. However, the ISCHEMIA trial results might stem fro...
Source: The Journal of Invasive Cardiology - Category: Cardiology Tags: J Invasive Cardiol Source Type: research
Reduced expression of the key regulator of cardiac metabolism, transcription factor PPAR α, in surgical samples of the auricles from patients with coronary heart disease and heart failure was detected by real-time quantitative PCR. These changes indicate reduced activity of this factor and a shift of energy metabolism from oxidative phosphorylation to glycolysis typical of dedifferenti ated cells. Electron microscopy revealed dedifferentiated cardiomyocytes with disassembled contractile apparatus and disorganized sarcomeres. In the examined specimens from patients with heart failure, severe myocardial fibrosis was revealed.
Source: Bulletin of Experimental Biology and Medicine - Category: Biology Source Type: research
Conclusion: MHR is significantly associated with CVD in COPD patients. Further prospective studies are warranted to elucidate the predictive value of MHR in COPD patients.
Source: Nigerian Journal of Clinical Practice - Category: Rural Health Authors: Source Type: research
AbstractAimsTo evaluate the risk of heart failure (HF) in patients with type 2 diabetes (T2D) complicated by development of intercurrent ischaemic heart disease (IHD), end ‐stage renal disease (ESRD), or both, compared to patients with T2D and no IHD and ESRD.Methods and resultsFrom Danish nationwide registries, we identified all patients with new ‐onset T2D with no history of HF between 1998 and 2015. Landmark analyses were used to estimate the 5‐year absolute risk of HF at several follow‐up times, and accounted for the occurrence of IHD and ESRD, identified before HF. The Aalen–Johansen estimator was used ...
Source: European Journal of Heart Failure - Category: Cardiology Authors: Tags: Research Article Source Type: research
AbstractPulmonary artery aneurysm (PAA) is a common finding in patients with long-term pulmonary arterial hypertension (PAH). The influence of PAH severity in the development of PAA remains unclear. We sought to determine whether PAA development is related to PAH severity and whether treatment optimization based on risk profile estimation is effective to stop pulmonary artery (PA) enlargement. This is a retrospective study of 125 PAH patients who underwent an imaging test (computed tomography or magnetic resonance) combined with a right heart catheterization within a six-month period. A multivariate analysis was performed ...
Source: Heart and Vessels - Category: Cardiology Source Type: research
CONCLUSION: Current data imply that PCI for CCS does not improve outcomes in a large percentage of cases. A symptomatic benefit exists only in patients with frequent angina pectoris. The selection of CCS patients for PCI needs to be more strictly bound to the recommendations of current guidelines, particularly in Germany. PMID: 32234189 [PubMed - in process]
Source: Deutsches Arzteblatt International - Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research
Publication date: Available online 2 April 2020Source: Revista Española de Cardiología (English Edition)Author(s): José María Oliver Ruiz, Laura Dos Subirá, Ana González García, Joaquín Rueda Soriano, Pablo Ávila Alonso, Pastora Gallego, on behalf of the Spanish Adult Congenital Heart Disease Network (RECCA)
Source: Revista Espanola de Cardiologia - Category: Cardiology Source Type: research
Authors: Arita Y, Tanaka K, Kitabayashi K, Hasegawa S PMID: 32238728 [PubMed - as supplied by publisher]
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
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