Effects of smoking and asthma in pregnant women

Asthma is a heterogeneous disease with risk factors inclusive of intrinsic (genetic predisposition) and extrinsic variables (environmental exposures) in early life. Studies have postulated towards probable adverse effects on maternal and child health owing to asthmatic status of the mother and in utero exposure to smoke.The ELFE cohort aimed to describe the characteristics of asthmatic and smoking mothers and compare them to non smoking non asthmatic mothers.16,030 mothers and infants were enrolled from the general population in 2011. Interviews were conducted for collection of the variables. A descriptive analysis followed by a univariate analysis of asthmatic and smoker mothers was performed.Asthmatic women who smoked were younger (29.3 years vs 31.1 p
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Epidemiology Source Type: research

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BPA exposure may activate an immune system response linked to asthma that is passed down through generations, according to a study published in the journal ofProteome Research.Science Daily
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
Authors: Fontes MAP, Marzano LAS, Silva CC, Silva ACSE Abstract Despite the current availability of safe and efficient drugs for treating hypertension, a substantial number of patients are drug-resistant hypertensives. Aiming this condition, a relatively new approach named catheter-based renal denervation was developed. We have now a clinically relevant time window to review the efficacy of renal denervation for treating this form of hypertension. This short review addresses the physiological contribution of renal sympathetic nerves for blood pressure control and discusses the pros and cons of renal denervation pro...
Source: Jornal Brasileiro de Nefrologia - Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
The Pharmacogenomics Journal, Published online: 17 January 2020; doi:10.1038/s41397-019-0140-yPharmacogenomic associations of adverse drug reactions in asthma: systematic review and research prioritisation
Source: The Pharmacogenomics Journal - Category: Drugs & Pharmacology Authors: Source Type: research
Source: CardioVascular and Interventional Radiology - Category: Radiology Source Type: research
Publication date: Available online 16 January 2020Source: Best Practice &Research Clinical GastroenterologyAuthor(s): Amihai Rottenstreich, Ariella Bar-Gil ShitritAbstractInflammatory bowel diseases (IBD) are commonly diagnosed in women of childbearing age. As such, pregnancy is often encountered in this subset of patients. Management of pregnancy in IBD patients poses numerous challenges as ensuring the safety of the mother and the fetus is required. Disease remission prior to pregnancy is a key determinant of both the course of IBD throughout gestation and pregnancy outcome. Thus, adequate preconception care is of pa...
Source: Best Practice and Research Clinical Gastroenterology - Category: Gastroenterology Source Type: research
Stroke risk factors are also increasing in young women and more needs to be done to identify and treat high-risk patients in early pregnancy, authors of a new study urge.Medscape Medical News
Source: Medscape Neurology and Neurosurgery Headlines - Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news
Long-term antipsychotic use is associated with substantially decreased mortality compared with no antipsychotic use, especially among patients treated with clozapine, according to areport inWorld Psychiatry, the journal of the World Psychiatric Association.Moreover, long ‐term antipsychotic use does not increase the likelihood that a patient will experience severe illness leading to hospitalization, wrote Heidi Taipale, Ph.D., of the Karolinska Institute in Sweden and colleagues.People with schizophrenia have a shorter average life expectancy than the general population. Taipale and colleagues wanted to know if these dif...
Source: Psychiatr News - Category: Psychiatry Tags: antipsychotics death Heidi Taipale hospitalization long-term use schizophrenia side effects suicide World Psychiatry Source Type: research
Authors: Eusebio M, Kraszula L, Kupczyk M, Kuna P, Pietruczuk M Abstract Preliminary studies demonstrated the potential role of CD8+CD25+ T regulatory cells (Tregs) in asthma. However, published data with regard to the relevance of signaling pathways that govern Tregs homeostasis are limited and conflicting. The first aim of this study was to characterize the phosphorylation of STAT-5 in CD8+CD25+ Tregs. The second aim was to investigate the ability of CD8+CD25+ Tregs from patients and controls to respond to interleukin (IL)-2 treatment in vitro. Twenty-five healthy subjects (NC) and 50 patients with either severe ...
Source: Journal of Biological Regulators and Homeostatic Agents - Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research
Publication date: Available online 15 January 2020Source: American Heart JournalAuthor(s): Sean van Diepen, Wayne Tymchak, Erin A. Bohula, Jeong-Gun Park, Lori B. Daniels, Nicholas Phreaner, Christopher F. Barnett, Benjamin B Kenigsberg, Andrew DeFilippis, Narayana Sarma Singam, Gregory W. Barsness, Jacob C. Jentzer, Bradley Ternus, David A. Morrow, Jason N. Katz, Critical Care Cardiology Trials Network InvestigatorsBackgroundThe prevalence of renal disease in cardiac intensive care units (CICUs) is increasing, but little is known about the utilization, concurrent therapies, and outcomes of patients requiring acute renal r...
Source: American Heart Journal - Category: Cardiology Source Type: research
Publication date: Available online 15 January 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Rory Chan, Chris RuiWen Kuo, Brian Lipworth
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
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