Late Breaking Abstract - Inflammation and metabolic syndrome exacerbate pulmonary hypertension associated with left heart disease

Conclusions: We developed a new preclinical model of Group 2 PH and showed that MetS exacerbates SAB-induced PH-LHD. We displayed that IL-6 promotes SAB-induced pulmonary vascular remodeling and PH-LHD. We proposed IL-6 as a therapeutic target in Groups 2 PH

Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Ranchoux, B., Nadeau, V., Breuils-Bonnet, S., Omura, J., Andre, M., Dupuis, J., Pibarot, P., Paulin, R., Boucherat, O., Provencher, S., Archer, S. L., Bonnet, S., Potus, F. Tags: Right ventricle Source Type: research