The growing role of flexible therapheuticbroncoscopy

Interventional pulmonology procedures have been performed traditionally with rigid bronchoscopy (RB), however flexible bronchoscopy (FB) is now on the rise. Sample of therapeutic bronchoscopies (TB) performed between 2017-2018 (n=57) predominantly in males (84%), with a mean age of 61.3 years. Most frequent indications were: central airway desobstructive treatment (DT) (n=16), endobronchial (E) brachytherapy (n=16), location and endoscopic closure of bronchopleural fistula (n=10), distal airway DT (n=5) and endobronchial foreign bodies extraction (n=3).77% of the procedures were performed exclusively with FB -group A-, while the remaining 23% -group B- used combined procedures of RB + FB. No statistically significant differences were found neither between the procedure success nor the complications when comparing the E treatment and the type of BT performed (p
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Interventional pulmonology Source Type: research

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Publication date: Available online 25 January 2020Source: Clinics and Research in Hepatology and GastroenterologyAuthor(s): Wen-Yi Liu, Jian-Hong Wang, Yuan Guo, Xin Wang, Xiao-Dong Wu, Chuan-Shen Xu, Yang Zhao, Yun-Jin ZangSummaryBackgroundAn objective and accurate evaluation of liver grafts is required to improve the prognosis of liver transplant recipients and to increase the number of available liver grafts.AimTo compare outcomes using FibroScan with that of pathology in liver grafts from brain-dead donors (DBD).MethodsLiver grafts from 52 DBD were examined using ultrasound (US), FibroScan before liver transplantation ...
Source: Clinics and Research in Hepatology and Gastroenterology - Category: Gastroenterology Source Type: research
ConclusionSLN biopsy with preoperative CTL and intraoperative ICG fluorescence imaging is a feasible and reliable procedure, without radioisotope tracers, for neck management in cases of early tongue cancer.
Source: Journal of Cranio Maxillofacial Surgery - Category: ENT & OMF Source Type: research
Publication date: Available online 25 January 2020Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): H. Saghafi, P. Benington, A. AyoubAbstractThe aim of this study was to compare the impact that the orthodontics-first approach and the surgery-first approach have on quality of life, anxiety, and depression in patients treated for dentofacial deformities. Data were collected on 32 patients (aged 17–47 years) who were all treated at a single multidisciplinary orthognathic clinic. They completed a 22-item Orthognathic Quality of Life Questionnaire (OQLQ), a seven-item Generalised Anxiety Disorder (GAD-7...
Source: British Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Source Type: research
ConclusionCongenital piriform sinus fistula is an important cause of deep neck abscess in children. The presence of purulent gas-liquid equilibrium or air shadow in cervical-enhanced computed tomography or ultrasound suggests a high possibility of the presence of an internal fistula, and endoscopic low temperature ablation can be done at the same time as the diagnostic endoscopy.ResumoIntroduçãoA fístula congênita do seio piriforme é uma doença relativamente rara na prática clínica; a maioria se manifesta na infância; entretanto, os médicos geralmente t&ec...
Source: Brazilian Journal of Otorhinolaryngology - Category: ENT & OMF Source Type: research
ConclusionsPillar suture combined with tonsillectomy may reduce postoperative bleeding incidence despite increasing pillar edema in pediatric tonsillectomy. Postoperative pain-relief, palatal hematoma, palatal discomfort sensation, site infection, and velopharyngeal insufficiency were not significantly altered compared to tonsillectomy alone. However, further studies are needed to corroborate the results of this study.ResumoIntroduçãoDiversas técnicas cirúrgicas têm sido utilizadas na tonsilectomia no intuito de reduzir complicações.ObjetivosAvaliar os efeitos da sutura dos p...
Source: Brazilian Journal of Otorhinolaryngology - Category: ENT & OMF Source Type: research
Publication date: January–February 2020Source: Brazilian Journal of Otorhinolaryngology, Volume 86, Issue 1Author(s): Manal Al Bin Manie, Khalid Hussain Al-Qahtani, Ahmed Al Ammar, Tahera Islam, Faiza N. Al Otaibi
Source: Brazilian Journal of Otorhinolaryngology - Category: ENT & OMF Source Type: research
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Source: Brazilian Journal of Otorhinolaryngology - Category: ENT & OMF Source Type: research
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Source: Brazilian Journal of Otorhinolaryngology - Category: ENT & OMF Source Type: research
ConclusionsIn conclusion, we identified a genetic regulator of spontaneous lipolysis, and provide evidence for HIF3A as a novel key regulator of lipolysis in subcutaneous adipoctyes as the mechanism through which the locus is influencing adipose tissue biology.
Source: Molecular Metabolism - Category: Endocrinology Source Type: research
Publication date: Available online 25 January 2020Source: Molecular and Cellular EndocrinologyAuthor(s): Ayelén Melisa Blanco, Juan Ignacio Bertucci, Cristina Velasco, Suraj UnniappanAbstractGrowth differentiation factor 15 (GDF-15), an anti-inflammatory and anti-tumorigenic cytokine, has been emerging as a regulator of appetite and energy homeostasis in mammals. In fish, the physiological role of this peptide remains to be elucidated. This research aimed to determine the possible role of GDF-15 on food intake in goldfish (Carassius auratus). To achieve our objectives, we first obtained a 595 bp gdf-15 cDNA sequence...
Source: Molecular and Cellular Endocrinology - Category: Endocrinology Source Type: research
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