Prevention of adverse reactions due to pharmacotherapy in MRTB considering polymorphism of glutathione-S-transferase M1 and T1genes

Conclusions: Deletion in the promoter area of the analyzed genes increases the risk of adverse reactions to antimycobacterial drugs and reduces the effectiveness of treatment in patients with MDR TB by 16.6 times [OR = 24,50, 95% CI OR: 2,18-142 64, p = 0.009].

Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Semianiv, I., Todoriko, L., Sprynsian, T., Yeremenchuk, I. Tags: Tuberculosis Source Type: research