Sex hormones and asthma in a nationwide study of U.S. adults

Conclusions: In a sample of U.S. adults, a high estradiol or testosterone level was linked to lower odds of asthma in post-PM obese females. A high estradiol was also associated with fewer asthma exacerbations in females.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Epidemiology Source Type: research

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Publication date: Available online 25 January 2020Source: Aquatic ToxicologyAuthor(s): Christine Dépatie, Magali Houde, Jonathan VerreaultAbstractLipids play important roles in growth, reproduction, locomotion, and migration of fish. Municipal effluents, which are complex mixtures of biological and chemical compounds including flame retardants, have been shown to alter lipid metabletabolism in environmentally and experimentally exposed fish. Down-regulation of several genes coding for fatty acid metabolism enzymes has previously been reported in male northern pike (Esox lucius) collected in the St. Lawrence River (Q...
Source: Aquatic Toxicology - Category: Toxicology Source Type: research
Publication date: Available online 25 January 2020Source: Preventive MedicineAuthor(s): Ying Lau, Daniel Guang Hui Chee, Xue Ping Chow, Ling Jie Cheng, Suei Nee WongAbstractGiven that many existing electronic health (eHealth) interventions with a general approach have limited effects, a personalised approach is necessary. We aimed to evaluate the effectiveness of personalised eHealth interventions in reducing body weight and identify the effective key features of such interventions. We searched seven databases for randomised controlled trials (RCTs) from inception until September 6, 2018. Of the 26,733 records identified, ...
Source: Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Publication date: Available online 25 January 2020Source: Journal of Vascular Surgery: Venous and Lymphatic DisordersAuthor(s): Steven M. Dean, Elizabeth Valenti, Karen Hock, Julie Leffler, Amy Compston, William T. AbrahamAbstractBackgroundLower extremity lymphedema is frequently encountered in the vascular clinic. Established dogma purports that cancer is the most common cause of lower extremity lymphedema in Western countries, whereas chronic venous insufficiency (CVI) is often overlooked as a potential cause. Moreover, lymphedema is typically ascribed to a single cause, yet multiple causes can coexist.MethodsA 3-year re...
Source: Journal of Vascular Surgery: Venous and Lymphatic Disorders - Category: Surgery Source Type: research
We examined the effects of the independent and combined effects of Zataria Multiflora supplementation and circuit resistance training (CRT) on selected adipokines among postmenopausal women. Forty-eight postmenopausal women were divided into four groups: Exercise (EG, n = 12), Zataria Multiflora (ZMG, n = 12), exercise and Zataria Multiflora (ZMEG, n = 12), and control (CG, n = 12). Participants in experimental groups either performed CRT (3 sessions per week with intensity at 55% of one-repetition maximum) or supplemented with Zataria Multiflora (500 mg every day after breakfast with 100 ml of water), or their combination...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Conclusions In conclusion, articles in this Research Topic made a very significant contribution to our understanding of the role played by environmental factors, dysbiotic conditions, and infections in triggering diseases. Since this is a rapidly expanding area of research, many other factors contributing to the onset of these diseases are not covered here. We are confident, however, that further studies will expand the list as well as bring a better understanding of mechanisms involved in the onset of autoimmune and autoinflammatory diseases. Author Contributions All authors listed have made a substantial, direct and i...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Conclusions: Long-term exposure to NO2 and road traffic noise was associated with higher risk of heart failure, mainly among men, in both single- and two-pollutant models. High exposure to both pollutants was associated with highest risk. https://doi.org/10.1289/EHP1272 Received: 25 October 2016 Revised: 09 August 2017 Accepted: 09 August 2017 Published: 26 September 2017 Address correspondence to M. Sørensen. Diet, Genes and Environment, Danish Cancer Society, Strandboulevarden 49, 2100 Copenhagen, Denmark. Telephone: +45 35257626. Email: mettes@cancer.dk Supplemental Material is available online (https://doi...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
In conclusion, low serum vitamin D is not significantly and independently related to female UI after propensity score matching in representative Korean data. PMID: 28244294 [PubMed - in process]
Source: Journal of Korean Medical Science - Category: Biomedical Science Tags: J Korean Med Sci Source Type: research
Conclusion: Menopause transition is not associated with changes in asthma incidence in women with natural menopause not using hormonal treatment. A surgical menopause could increase the risk of asthma onset. Crude incidence rates of asthma according to menopauseMHT never usersMHT ever usersEventPYIncidence (95% CI)EventPYIncidence (95% CI)before menopause118826771.43 (1.17-1.69)1311022461.28 (1.06-1.50)after natural menopause1691326441.27 (1.08-1.46)4733230351.46 (1.33-1.59)after surgical menopause42238591.76 (1.23-2.29)82385852.13 (1.67-2.59)
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: 6.1 Epidemiology Source Type: research
Conclusion: Most patients with asthma which first-time onset in peri-MP period had a climacteric syndrome, which impairs the patients quality of life. HRT effectively reduces menopausal disorders, had a positive influence on asthma.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: 1.11 Clinical Problems - Asthma Source Type: research
Abstract Asthma is more prevalent and more severe in older individuals. Here, we review the literature on asthma in the elderly, with special focus on the pathophysiologic and immunologic mechanisms, healthcare utilization, the role of menopause and obesity, and the impact of chronic asthma on biological aging. Aging of the lung is characterized by constant decline in lung function, which is accelerated by occupational or tobacco exposure and pollution that may contribute to new onset asthma or greater severity of asthma in the elderly. Gender and sex hormones are critical determinants of asthma severity, such tha...
Source: Current Geriatrics Reports - Category: Geriatrics Source Type: research
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