Salbutamol and ipratropium bromide are high risk factors for atrial arrhythmias in patients with COPD and CVS diseases

In this study, ECGs were evaluated before and after the usage of salbutamol and ipratropium bromide. Patients were evaluated before and after 4 weeks of treatment :1) salbutamol, 90 mcg 1 puffs every 4 hours 2) Ipratropium Bromide, 34 mcg 2 puffs every 6 hours. ECGs performed pre-treatment and at 4th Week. We were able to find various arrhythmias such as atrial tachycardia, atrial fibrillation and ventricular tachycardia. 60 ECGs recordings in 30 treated patients (M=F). Out of 30 patients, ECG changes recorded in 28 patients. The most common met ECG was with atrial tachycardia in 20 patients out of which 12 were females (60%) and 8 were males (40%). The least seen was atrial fibrillation in only one male patient. The ventricular tachycardia was seen in 6 males and 1 female patient. The percentage of patients with atrial tachycardia, post usage of the drugs mentioned was significantly higher with 71.4%, which is way higher than other types of arrhythmias occurred 3.57%(AF), 25%(VT) respectively.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Airway pharmacology and treatment Source Type: research