Different inhaled corticosteroids altered lung microbiome and regulating the expression of PAF receptor as well as the phagocytosis function of macrophage

Conclusions: Our study demonstrated all ICS-treated mice reduce airway inflammation. Different ICS selected different lung microbiome, though they had similar influences on phagocytosis function of macrophage and the PAFr expression.

Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Chen, Y.-F., Hou, H.-H., Cheng, S.-L., Wang, H.-C., Yu, C.-J. Tags: Airway cell biology and immunopathology Source Type: research