The role of obesity in patients with sarcoidosis
Introduction: Fat tissue produced inflammatory cytokines which have an impact on systemic diseases such as sarcoidosis(S). Treatment with corticosteroids(CS) can worsen metabolic disoders and patients’ life qualityAim: to assess the role of obesity in clinical aspect of SMethods: 142 patients with S were observed at pulmonology depratment Tareev Clinic. BMI was calculated before treatment was start. Patients were divided into 2groups:gr.1-with obesity(BMI≥30kg/m2)(n=84),gr.2-without obesity(n=58). Control group consisted of 35 patients with chonic bronchitis and obesityResults: There was prevelance of middle aged women with obesity among patients with S. Male patients were charecterised by younger age and lower BMI. Obesity in patients with S was significantly(p
CONCLUSION: Hospitalization or death was not influenced by the type of RO, Al accumulation, or TMV classification. An elevated prevalence of osteoporosis and Al accumulation was detected. PMID: 31967202 [PubMed - as supplied by publisher]
This study aimed to determine the effect of the consumption of peel flour or pulp flour from two varieties of Solanum tuberosum (Yungay potato and Canchán potato) on the accumulation of adipose tissue, organ weight, and oxidative stress in the liver of rats. We carried out an experimental study in 24 obese Holtzman rats, divided into four groups and subjected to diets containing 10% flour from both varieties of potato. The groups were T1: Yungay peel; T2: Yungay pulp; T3: Canchán peel; and T4: Canchán pulp. When the study was completed, all the animals were slaughtered to record the weights of organs a...
Authors: Lancellotti P, De Pauw M, Claeys M Abstract Cardiovascular disease (CVD) and cancer represent the two main causes of death in industrialised countries. Both share common risk factors (diabetes, obesity, hypertension, diet, smoking, etc.). The associated timing of CVD and cancer onset is thus largely influenced by modifiable risk factors. Advances in cancer treatment have extended the lives of patients with cancer, but for some at the cost of adverse cardiovascular events. The rapidly growing number of patients surviving cancer, often in the setting of advanced age, new or pre-existing CV disease and risk f...
In conclusion, endogenous ghrelin system could be considered as a new target or treatment for metabolism disorders, cardiac diseases, neurodegenerative diseases, and tissue injuries.
In conclusion, our diagnostic prediction model uses easily obtainable information to identify children at increased risk of high blood pressure, offering an opportunity for targeted screening. This model enables to detect a higher proportion of children with high blood pressure than a strategy based on child overweight only.
Publication date: Available online 22 January 2020Source: Annals of Physical and Rehabilitation MedicineAuthor(s): Maxime Boidin, Anil Nigam, Valérie Guilbeault, Elise Latour, Antoine Langeard, Martin Juneau, Mathieu Gayda
Physical activity is established as being instrumental in improving physical as well as mental health of not only healthy children but also children with chronic diseases. When good physical activity habits are established in childhood they become habitual and help the development of long-term cardiovascular health in adults. All children should be physically active in order to reduce or perhaps even help prevent childhood obesity. The current recommendations of the WHO call for at least 60 minutes of moderate to vigorous intensity physical activity daily.
ConclusionsA higher intake of hydroxycinnamic acids, especially from chlorogenic acids—present in coffee, fruits, and vegetables—was associated with a lower incidence of breast cancer among postmenopausal women. Future observational studies are needed to corroborate these results.
Publication date: Available online 22 January 2020Source: The Lancet NeurologyAuthor(s): Jeremy Chataway, Floriana De Angelis, Peter Connick, Richard A Parker, Domenico Plantone, Anisha Doshi, Nevin John, Jonathan Stutters, David MacManus, Ferran Prados Carrasco, Frederik Barkhof, Sebastien Ourselin, Marie Braisher, Moira Ross, Gina Cranswick, Sue H Pavitt, Gavin Giovannoni, Claudia Angela Gandini Wheeler-Kingshott, Clive Hawkins, Basil SharrackSummaryBackgroundNeurodegeneration is the pathological substrate that causes major disability in secondary progressive multiple sclerosis. A synthesis of preclinical and clinical re...
This study deepens our understanding of the mechanisms of podocyte loss in DN and shows targeting ANGPTL4-related signaling has therapeutic potential for DN.