Prognostic factors and surgical resection of pulmonary metastases from colorectal cancer

Benefits of 5-year survivals after pulmonary metastasectomy of colorectal carcinoma range from 21% - 62%. Selection criteria were completely resectable lesions in the lung, lesions < 10 cm seen on CT scan, no other metastatic disease, resected primary colorectal tumor – the primary site is controlled, no suspicion of mediastinal lymph node metastases, good performance score (WHO 0-2), sufficient lung function and no contraindication due to concomitant disease. This was retrospective study, period from 2008 – 2018, in total 78 patients. Time since primary surgery < 36 months = 54, 69%, > 36 months = 24, 31%. Median DFI = 29.3 months (0-79 m.). Single metastasis in 41, 53 %, multiple in 37,47 %. Tumor size was from 0.8 to 8 cm with median size 1.83 cm, < 3 cm 22,28 % and > 3 cm 56,72 %. Total number of pulmonary meatsectomies 111, first operation in 15,14 %, repeted in 96,86 %. Type of resecton :wedge 63,57%, segmentectomy 20,18 %, lobectomy 16.14 %. Mediastinal lymph node metastasis were found in 14.18 %, without lymph node metastasis in 64.82%. Probability of survival for patiens who satisfied all favorable factors ( CEA serum level ), favorable characteristics: 21 pts = 26,9%, survival rates 5 years. and 10 years: 65% and 43%. Without all favorable characteristics: 57 pts = 73.1%, survival rates 5 y. and 10 y.:16% and 10%. Prognosis-related criteria for surgery appear to be:status of lymph nodea, serum carcinoembryonic antigen level before metastas...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Thoracic surgery Source Type: research