Late Breaking Abstract - Pneumonectomy in patients with reduced pulmonary function: complications and 30-day mortality

We report our series of patients with low pulmonary function undergoing PNs. Sixty-one patients with preoperative FEV1 less than 50% of predicted were included. The mean percentage of preoperative and postoperative predicted FEV1 were 46% and 35% respectively. In 27 patients (44.2%) no data about maximal oxygen consumption were available. Mean age was 58.3±9.4 years. Twelve patients (19.6%) underwent induction therapy and 14 patients (22.9%) had previous cardiovascular diseases. We performed 28 right PNs (45.9%) and in 13 patients (21.3%) an extended resection was required. Two patients (3.2%) died in the perioperative period due to sudden cardiac failure. Five patients (8.1%) showed severe respiratory failure requiring admission to the intensive care unit (1 tracheostomy). No patient was discharged with supplemental oxygen. Seventeen patients (27.8%) had atrial fibrillation (15 converted pharmacologically, 2 electrically). Three patients (4.9%) had early bronchial dehiscence: one underwent immediate surgical repair, 2 were treated with airway prosthesis deployment and repeated pleural lavage. Two patients (3.2%) were readmitted within 30 days for respiratory failure due to contralateral pneumonia successfully treated with antibiotics and non-invasive ventilation. Older age (p=0.02), induction therapy (p=0.003) and previous cardiac disorders (p=0.004) increased the risk of complications. Overall 5-year survival was 64%. Although in this setting PN is often controindica...

Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Poggi, C., Diso, D., Mantovani, S., Maurizi, G., Carillo, C., Pecoraro, Y., Pagini, A., Bassi, M., Amore, D., Cagnetti, S., Mottola, E., De Giacomo, T., Rendina, E. A., Venuta, F., Anile, M. Tags: Thoracic surgery Source Type: research