Comparison of efficacy and safety of fixed-dose combination regimen versus separate drugs for treatment of tuberculosis

Conclusion: The reviewed studies showed that four-drug fixed-dose combination therapy provides greater patient comfort by reducing the number of pills as well as simplifying pharmaceutical management. However, the composition and dosage recommendations for fixed-dose combination formulations differ from those for separate formulations. Thus, questions about the effectiveness and side effects of combination formulations remain.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Paediatric bronchology Source Type: research