Pulmonary alveolar proteinosis due to heterozygous mutation in OAS1: Treatment of a novel disease with whole lung lavages and stem cell transplantation

Conclusion: WLL in patients with pulmonary alveolar proteinosis can stabilize patients until a definitive diagnosis can be made. Bone marrow transplantation may cure PAP due to a mutation in the OAS1 gene.

Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Seidl, E., Magg, T., Reiter, K., Schramm, D., Kappler, M., Pawlita, I., Ripper, J., Feilcke, M., Nübling, J., Ley-Zaporozhan, J., Krüger-Stollfuss, I., Kammer, B., Walz, C., Reu, S., Meino, R., Klein, C., Hauck, F., Griese, M. Tags: Paediatric respiratory infection and immun. Source Type: research