Using sputum proteomics to develop a test for reflux aspiration in cystic fibrosis patients

Conclusion: These data suggest the sputum proteome of CF subjects may be influenced by gastro-oesophageal reflux. Although this appears to support a relationship between reflux and CF lung disease, it is not currently possible to conclude if this is a consequence of reflux aspiration. We aim to further explore these proteome differences, with the eventual aim of developing a protein biomarker for diagnosis of reflux aspiration.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Cystic fibrosis Source Type: research