Obstructive sleep apnoea and liver steatosis as measured by magnetic resonance in patients with metabolic comorbidities

Conclusion: severe OSA conferred a significant increase in risk for liver steatosis but the association was not maintained after adjusting for confounders.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Sleep and control of breathing Source Type: research

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ConclusionHigh levels of lifestyle-related cancer-risk behaviors were found in most of the Hong Kong construction workers studied. The present study contributes to understanding how cancer-related lifestyle risk behaviors cluster among construction workers and relative impact factors of risk behaviors. It is essential to tailor health behavior interventions focused on multiple risk behaviors among different groups for further enlarging the effects on cancer prevention.
Source: Safety and Health at Work - Category: Occupational Health Source Type: research
Publication date: Available online 21 January 2020Source: European UrologyAuthor(s): Jae Heon Kim, In Gab Jeong
Source: European Urology - Category: Urology & Nephrology Source Type: research
BACKGROUND: Family history (FH) is an important risk factor for the development of alcohol use disorder (AUD). A variety of dichotomous and density measures of FH have been used to predict alcohol outcomes; yet a systematic comparison of these FH measures ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Conclusion: The present study demonstrated an association between fibrosis, a finding of worse prognosis in patients with NAFLD, and moderate to severe OSA, regardless of obesity.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Sleep and control of breathing Source Type: research
Authors: Damaskos C, Garmpis N, Kollia P, Mitsiopoulos G, Barlampa D, Drosos A, Patsouras A, Gravvanis N, Antoniou V, Litos A, Diamantis E Abstract The globalization of the Western lifestyle has resulted in a dramatic increase of diabetes mellitus, a complex, multifactorial disease. Diabetes mellitus is a condition often associated with disorders of the cardiovascular system. It is well established that three quarters of diabetics, aged over 40, will die from cardiovascular disease and are more likely than non-diabetics to die from their first cardiovascular event. Therefore, risk stratification is necessary to ind...
Source: Current Cardiology Reviews - Category: Cardiology Tags: Curr Cardiol Rev Source Type: research
Publication date: Available online 25 July 2019Source: Journal of Clinical and Experimental HepatologyAuthor(s): Raseen Tariq, Page Axley, Ashwani SingalAbstractNon-Alcoholic Fatty Liver Disease (NAFLD) is now the leading cause of chronic liver disease worldwide with a strong association with metabolic syndrome. NAFLD is truly a systemic disease and is associated with a plethora of extra-hepatic manifestations or comorbidities. These are either related to secondary effects of associated obesity or from pathophysiological effects of insulin resistance in NAFLD. Three most common causes of increased morbidity and mortality a...
Source: Journal of Clinical and Experimental Hepatology - Category: Gastroenterology Source Type: research
Abstract Lipoprotein (a) [Lp(a)] is an independent but moderate, predictor for coronary heart disease (CHD) prevalence and severity. Several established and emerging cardiovascular (CV) risk factors including age, gender, ethnicity, smoking, dyslipidemia, hypertension, obesity, type 2 diabetes mellitus, alcohol consumption, arterial stiffness and hyperuricemia have been linked to Lp(a) metabolism. Apart from CHD, Lp(a) has been also associated with non-cardiac vascular diseases and diseases associated with increased CV risk such as chronic kidney disease, metabolic syndrome, non-alcoholic fatty liver disease, erec...
Source: Current Medicinal Chemistry - Category: Chemistry Authors: Tags: Curr Med Chem Source Type: research
Non-Alcoholic Fatty Liver Disease (NAFLD) is now considered as the hepatic component of metabolic syndrome. Its prevalence, paralleling the growing diffusion of obesity and type II diabetes, is increasing worldwide both in adults and children. NAFLD is estimated to affect up to 30% of the general population in Western countries, reaching an even higher prevalence among diabetic and obese individuals [1,2]. From 20 to 30% of NAFLD patients are expected to develop non-alcoholic steatohepatitis (NASH), characterized by steatosis, parenchymal damage, lobular/portal inflammation with or without perisinusoidal and/or portal fibrosis.
Source: Journal of Hepatology - Category: Gastroenterology Authors: Tags: Editorial Source Type: research
Authors: Frija-Orvoën E Abstract Strongly linked to the presence of obesity, the obstructive sleep apnea syndrome is an independent risk factor for abnormalities of glucose metabolism ranging from simple impaired glucose tolerance to type 2 diabetes. It is also a risk factor for dyslipidemia, metabolic syndrome and non-alcoholic fatty liver disease. The pathological mechanisms underlying these associations remain to be precisely discovered, but intermittent hypoxia is probably one of the major factors. The place of obstructive apnea treatment in the management of metabolic conditions remains unclear....
Source: Revue des Maladies Respiratoires - Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research
Childhood overweight and obesity affect approximately 1/3 of US children. Many have one or more comorbidities such as abnormal blood pressure, dyslipidemia, non alcoholic fatty liver disease, metabolic syndrome, polycystic ovarian syndrome, pre-diabetes, diabetes, obstructive sleep apnea, psychological problems, impaired quality of life, as well as others. Treatment of childhood obesity can be time consuming, difficult and complex and many pediatric practices have limited resources to offer interventions within an office setting.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
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