Changes in objective markers following inhaled corticosteroids (ICS) in asthmatics with airway hyperresponsiveness (AHR) to mannitol

Conclusions: The difference, in commonly reported ICS sensitive parameters, was minimal between subjects with sustained AHR to mannitol and those whose AHR was abolished after 18wks of ICS. These findings suggest that measurements of asthma control, airway calibre and FeNO are not adequate to confirm optimal ICS therapy and the measurement of AHR to mannitol is a more useful guide to treatment with ICS.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Monitoring airway disease Source Type: research