Pre-metastatic niche triggers SDF-1/CXCR4 axis and promotes organ colonisation by hepatocellular circulating tumour cells via downregulation of Prrx1

Circulating tumour cells (CTCs), especially mesenchymal CTCs, are important determinants of metastasis, which leads to most recurrence and mortality in hepatocellular carcinoma (HCC). However, little is known ...

Source: Journal of Experimental and Clinical Cancer Research - November 21, 2019 Category: Cancer & Oncology Authors: Yujun Tang, Yishi Lu, Yuan Chen, Lei Luo, Lei Cai, Bangjian Peng, Wenbin Huang, Hangyu Liao, Liang Zhao and Mingxin Pan Tags: Research Source Type: research