Ex Vivo Evaluation of Mouse Brain Elasticity Using High-Frequency Ultrasound Elastography

Conclusion: The average shear moduli of the cortex and hippocampus were 3.84 and 2.33 kPa for the 4-month-old mice and 3.77 and 1.94 kPa for the 11-month-old mice, respectively. No statistical difference was observed in the cortex stiffness of mice of different ages. However, the hippocampus significantly softened with aging.
Source: IEEE Transactions on Biomedical Engineering - Category: Biomedical Engineering Source Type: research