Changes in resting state MRI networks from a single season of football distinguishes controls, low, and high head impact exposure.

Changes in resting state MRI networks from a single season of football distinguishes controls, low, and high head impact exposure. Proc IEEE Int Symp Biomed Imaging. 2017 Apr;2017:464-467 Authors: Murugesan G, Famili A, Davenport E, Wagner B, Urban J, Kelley M, Jones D, Whitlow C, Stitzel J, Maldjian J, Montillo A Abstract Sub-concussive asymptomatic head impacts during contact sports may develop potential neurological changes and may have accumulative effect through repetitive occurrences in contact sports like American football. The effects of sub-concussive head impacts on the functional connectivity of the brain are still unclear with no conclusive results yet presented. Although various studies have been performed on the topic, they have yielded mixed results with some concluding that sub concussive head impacts do not have any effect on functional connectivity, while others concluding that there are acute to chronic effects. The purpose of this study is to determine whether there is an effect on the functional connectivity of the brain from repetitive sub concussive head impacts. First, we applied a model free group ICA based intrinsic network selection to consider the relationship between all voxels while avoiding an arbitrary choice of seed selection. Second, unlike most other studies, we have utilized the default mode network along with other extracted intrinsic networks for classification. Third, we systematically tested mu...
Source: Proceedings - International Symposium on Biomedical Imaging - Category: Radiology Tags: Proc IEEE Int Symp Biomed Imaging Source Type: research