7+1 Ways Digital Health Technologies Help Fight Obesity

Obesity rates have nearly doubled in the last 20 years. Only in England, 13 million people over the age of 16 were considered obese in 2017, Daily Mail reported. According to an analysis of government data, the NHS spent a staggering £1.075 billion on type 2 diabetes treatment alone. And since obesity is linked to cardiovascular problems, diabetes, and some cancers, most of us live in countries where obesity kills more people than malnutrition. It’s preventable. It’s treatable. And yet numbers keep rising. So, what’s happening and what’s the solution? Let’s get digital! Ok, we may not have supernatural psychic abilities, but we’re pretty sure you’re reading this article while sitting. The technological innovations of the last century have led to an unhealthy, sedentary lifestyle (we only spend on average 3 hours a day on our feet) and a decrease in sport and other physical activities. This, combined with the food environmental changes, the aggressive marketing of fast food brands and sodas, and consequentially increased caloric intake play a huge role in the global obesity epidemic. And yet the key to turning this alarming situation around lies in technology, especially in digital health. Wearable sensors, gamification, educational support, and online counseling could change the challenging journey of weight loss with monitoring psychological, physical parameters, and offering personalized advice to patients. So what w...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Medicine Health Sensors & Trackers digital health digital technology digital health sensors weight management obesity weight loss Source Type: blogs

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Publication date: Available online 22 February 2020Source: Journal of Pharmaceutical AnalysisAuthor(s): Max Sauter, Philipp Uhl, Jürgen Burhenne, Walter E. HaefeliAbstractExenatide is the first approved glucagon-like peptide 1 receptor agonist subcutaneously or intramuscularly injected for the treatment of type 2 diabetes mellitus. Typical therapeutic plasma concentrations are in the low pg/mL range therefore requiring ultra-sensitive quantification. To enable the accurate evaluation of pharmacokinetic studies, we established a UPLC-MS/MS assay with a lower limit of quantification (LLOQ) of 5 pg/mL (1.2 pM) using 20...
Source: Journal of Pharmaceutical Analysis - Category: Drugs & Pharmacology Source Type: research
Conclusion: Taken together, these results suggest that SXD maybe alleviate EMT in DN via the inhibition of the TGF-β1/Smad/RUNX3 signaling pathway under hyperglycemic conditions.Graphical abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research
This study compared biointeractivity (pH of soaking water and calcium ions), porosity, water sorption, solubility, compressive strength, lap shear strength, as well as the apatite forming ability of three calcium silicate-based capping materials: Mineral trioxide aggregate (MTA), Biodentine (BD) and Tech Biosealer capping (BS).MethodsOne hundred and five discs of the tested materials were prepared in compliance with the manufacturer’s instructions. The materials' pastes were placed in Teflon molds and allowed to set before testing. The pH and Ca+2 ions were measured by a potentiometric method. Porosity, water sorptio...
Source: The Saudi Dental Journal - Category: Dentistry Source Type: research
Publication date: Available online 21 February 2020Source: NeurocomputingAuthor(s): Xuchu Wang, Suiqiang Zhai, Yanmin NiuAbstractAccurate left ventricle landmark localization in cardiac MRI plays a vital role in computer-aided diagnosis of heart disease. Typical classification models hardly deal with artifacts and low discrimination of landmark regions by using only local image information, while regression models suffer from ambiguity between random samples and label, also the imbalance of samples. To overcome this limitation, this paper proposes a left ventricle landmark localization and identification method in cardiac ...
Source: Neurocomputing - Category: Neuroscience Source Type: research
Authors: Di Lullo L, Bellasi A, Guastamacchia E, Triggiani V, Ronco C, Lavalle C, Di Iorio BR, Russo D, Cianciolo G, La Manna G, Settembrini S Abstract Diabetes mellitus, with its complications, is one of the major health problems in economically developed countries and its prevalence is constantly increasing. Kidneys and heart involvement represent main comorbidities in diabetic patients often leading to organ's failure. The treatments available until a few years ago are often associated with hypoglycemia, weight gain, gastro-intestinal disorders and other side effects together with serious averse effects on renal...
Source: Minerva Cardioangiologica - Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
Authors: De Vecchis R, Paccone A, Di Maio M Abstract BACKGROUND: The MacNew questionnaire in its original version is a diagnostic tool which consists of a number of questions answered on a seven-point scale. Among the multiple possible choices, each marked by a box, the examined patient will have to tick only one. In fact, more than one answer for each proposed question is not allowed, for the formulation of the final score. Global and subscale( physical, social and emotional subscales) scores are computed by dividing the sum of the scores achieved for each individual item by the number of items listed in the quest...
Source: Minerva Cardioangiologica - Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
Authors: De Vecchis R, Paccone A, Di Maio M Abstract INTRODUCTION: The guidelines of the Scientific Societies of Cardiology suggest limiting water intake in the diet as one of the non-pharmacological measures for the management of chronic heart failure. However, many patients with heart failure may suffer from severe thirst, even irrespective of a possible restricted fluid intake, and this has received relatively little attention in clinical studies. Moreover, definitive and irrefutable evidence that documents the efficacy of the limitation in water consumption on major cardiovascular outcomes is lacking. Therefore...
Source: Minerva Cardioangiologica - Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
CONCLUSIONS: The assessment of mitral apparatus in acute phase of MI can be most useful to determine the change of the degree of MR long-term post MI. Although LV remodelling itself contributes to IMR, this influence is directly dependent on alterations in mitral geometry. PMID: 32083424 [PubMed - as supplied by publisher]
Source: Minerva Cardioangiologica - Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
Authors: Cao M, Zhou M, Zhang J Abstract Patients with metastatic colorectal cancer (mCRC) beyond second line treatment have a poor prognosis. Regorafenib, TAS-102, fruquintinib, panitumumab and cetuximab are recommended single-agent chemotherapy regimens for patients exhibiting disease progression, this meta-analysis aimed to evaluate the efficacy and safety of these regimens in randomized controlled trials (RCTs). Eight RCTs with 3,832 cancer patients were included. Results showed that there was no significant difference in OS and PFS among the four drugs when comparing all patients or patients who have the KRAS ...
Source: Journal of Chemotherapy - Category: Cancer & Oncology Tags: J Chemother Source Type: research
CONCLUSION: The best of our knowledge it is the third description of brachial plexus schwannoma associated with breast cancer and the first with a synchronous association. The knowledge of this pathology and its potential to alter treatment justify the reporting of the present case. PMID: 32083563 [PubMed - as supplied by publisher]
Source: Breast Disease - Category: Cancer & Oncology Tags: Breast Dis Source Type: research
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