Chemical Stability and Antimicrobial Activity of Plasma-Sprayed Cerium Oxide–Incorporated Calcium Silicate Coating in Dental Implants

In this study, MC3T3-E1 cells cultured on the plastic, Ti-6Al-4V, and the cerium oxide–incorporated calcium silicate coatings (CeO2-CS) coating served as the blank, control, and CeO2-CS groups, respectively. A cell counting kit-8 (CCK-8) and flow cytometry were used to evaluate the biocompatibility. The osteoblastic differentiation of the MC3T3-E1 cells was also analyzed by quantitative real-time polymerase chain reaction analysis. The CCK-8 and counts of colony-forming units (CFUs) were used to detect the antibacterial activity of the coating on Enterococcus faecalis. The study showed that the cerium oxide–incorporated calcium silicate coating (CeO2-CS) has better biocompatibility. Meanwhile, the ALP, OCN, and BSP mRNA expression levels in the CeO2-CS group were significantly upregulated (P
Source: Implant Dentistry - Category: Dentistry Tags: Basic and Clinical Research Source Type: research