An overview of non-invasive imaging modalities for diagnosis of solid and cystic renal lesions

AbstractRenal imaging is an essential investigative tool and preliminary task for determining a suitable sanative option for the treatment of kidney cancer. In recent decades, with the increasing usage of abdominal imaging, there is an upsurge in the number of adrenal incidentalomas. Among these accidentally revealed lesions, most of them are complex that warrant immediate aggressive treatment planning due to their malignant potential. The guidelines given by the American Urological Association (AUA), American College of Radiology (ACR), and European Association of Urology (EAU) vary concerning the use of ideal preliminary imaging modality to investigate the patients with suspected flank pain, hematuria, or palpable mass in the abdomen. Initially, an effort has been made to discriminate cystic and solid renal lesions which are helpful in separating benign and malignant nature as different imaging patterns are observed on distinct imaging modalities for solid and cystic renal lesions. Various attempts have been made to improve the accuracy of cancer diagnosis by employing different imaging modalities. The primary aim of this article is to study the capabilities of different imaging techniques for detecting and differentiating solid and cystic lesions to facilitate treatment planning based on computed tomography (CT), ultrasonography (US), magnetic resonance imaging (MRI), positron emission tomography (PET), and optical coherence tomography (OCT). Further, the advantages, disad...
Source: Medical and Biological Engineering and Computing - Category: Biomedical Engineering Source Type: research

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ConclusionsWe conclude that abscesses of metastases could be a rare side effect occurring during treatment with pazopanib in patients with renal cancer.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
We present our single centre experience in transplanted patients and future candidates for transplantation. Methods: Retrospective analysis from an anonymised database of bilateral nephrectomies for ADPKD patients. Results were reported as median, range, and percentage. Differences between groups were tested using ANOVA and t-test. Surgery was performed between January 2012 and July 2018. Results: Thirty-three patients underwent bilateral native nephrectomy for APKD. 18 had a functioning kidney transplant (transplant group, 55%) while 15 patients were on dialysis (dialysis group, 45%) at the time of surgery; 8 pa...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
CONCLUSIONS: The single-port approach has advantages as easier surgical planning and transition for combined and multi-quadrants surgeries: faster recovery, minimal postoperative pain and need for opioids, and excellent cosmetic outcome. We suggest that combined procedures should be performed only in high volume institutions by surgeons with vast experience in robotic surgery in selected patients. PMID: 31864774 [PubMed - as supplied by publisher]
Source: Actas Urologicas Espanolas - Category: Urology & Nephrology Authors: Tags: Actas Urol Esp Source Type: research
CONCLUSION: The use of NSAIDs was not related to acute kidney injury, postsurgical complications, or prolonged hospital stay in patients with renal cancer undergoing nephrectomy. PMID: 31715614 [PubMed - as supplied by publisher]
Source: Oncology - Category: Cancer & Oncology Authors: Tags: Oncology Source Type: research
Abstract Hereditary leiomyomatosis and renal cell cancer is a genodermatosis with an autosomal dominant inheritance pattern. It is a tumour predisposition syndrome characterized by cutaneous and uterine leiomyomas, and increased susceptibility to develop renal cell cancer. There are 200-300 families with hereditary leiomyomatosis and renal cell cancer reported worldwide, but the syndrome is believed to be underdiagnosed. Cutaneous leiomyomas are small smooth muscle tumours that tend to grow over time. Larger lesions, in particular, can cause pain or itching. Uterine leiomyomas are highly penetrant feature in women...
Source: Acta Dermato-Venereologica - Category: Dermatology Authors: Tags: Acta Derm Venereol Source Type: research
Abstract Traditional cancer therapies, such as treatment with anthracyclines and chest radiation, are known to induce cardiovascular complications. Currently, the increase of cancer therapies will involve new mechanisms such as cancer immunotherapies, also called immune checkpoint inhibitors (PD-1, PD-L1 and CTLA-4 inhibitors). These treatments have shown long-term remissions in subgroup of cancers, including melanomas, non-small-cell lung cancer, urothelial carcinoma, renal cell carcinoma, squamous cell carcinoma of the head and neck and colorectal cancer. Although these treatments will change the natural course ...
Source: Bulletin du Cancer - Category: Cancer & Oncology Authors: Tags: Bull Cancer Source Type: research
Abstract Background and objectives: Microwave thermal ablation (MWT) is one of the treatment options for kidney cancer. However, for patients over 70 years old the safety and oncological efficacy of this treatment is still controversial. The goal of this study was to compare MWT with open partial nephrectomy (OPN) and to find out whether MWT is preferable in maintaining patient renal function and reducing the risk of postoperative complications. Materials and Methods: Depending on the treatment choice, all patients were divided into two groups: an MWT group and an open kidney resection (OPN) group. Data have been ...
Source: Medicina (Kaunas) - Category: Universities & Medical Training Authors: Tags: Medicina (Kaunas) Source Type: research
Conclusion: Among the PNS, only Stauffer's syndrome was significantly associated with poor outcome.
Source: Nigerian Journal of Clinical Practice - Category: Rural Health Authors: Source Type: research
Publication date: Available online 21 August 2019Source: Surgery (Oxford)Author(s): Gideon Blecher, Kara McDermott, Benjamin ChallacombeAbstractRenal carcinoma is a reasonably common cancer in the UK. Fortunately, its diagnosis is nowadays much earlier due to the increased utilization of radiological imaging. While surveillance is an option, particularly in older/comorbid patients, nephron-sparing surgery remains the gold standard treatment for small renal masses. Laparoscopic, robotic or open partial nephrectomy have excellent cure rates. For larger tumours, radical nephrectomy may be required. This again can be performed...
Source: Surgery (Oxford) - Category: Surgery Source Type: research
We report a case of a 63-year-old female admitted to the hospital due to abdominal pain, nausea, vomiting and elevated blood pressure. One month earlier, sunitinib therapy for metastatic renal cell carcinoma was initiated. During the first cycle of therapy, after three weeks of sunitinib 50 mg daily, symptoms started and she stopped taking the drug. At admission, laboratory tests revealed elevated serum and urine amylase, C-reactive protein, urea and creatinine, and lowered platelet and leukocyte counts and hemoglobin value. Urine test showed proteinuria, erythrocyturia, leukocyturia and granulated cylinder. The patient wa...
Source: Acta Clinica Croatica - Category: General Medicine Tags: Acta Clin Croat Source Type: research
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