SUMO3 modification by PIAS1 modulates androgen receptor cellular distribution and stability

Abnormal reactivation of androgen receptor (AR) signaling in castration-resistant prostate cancer (CRPC) mainly results from overexpression and down-regulation of AR. Sumoylation of AR can influence its functi...

Source: Cell Communication and Signaling - November 21, 2019 Category: Molecular Biology Authors: Nanyang Yang, Sitong Liu, Tian Qin, Xintong Liu, Nobumoto Watanabe, Kevin H. Mayo, Jiang Li and Xiaomeng Li Tags: Research Source Type: research