Spindle cell lesions of the breast: diagnostic issues

Spindle cell lesions of the breast encompass a broad spectrum of entities. In addition to breast-specific spindle cell lesions, soft tissue and cutaneous spindle cell lesions can also present in the breast. The prognosis and proper management of each entity varies considerably and thus calls for a systemic approach in diagnosis. A simple two-step approach is described in this review, where spindle cell lesions are classified into biphasic (with both spindle and epithelial components) and monophasic (spindle cell only) types, followed by histologic grading.

Source: Diagnostic Histopathology - November 19, 2019 Category: Pathology Authors: Joshua JX. Li, Gary M. Tse Tags: Mini-symposium: Breast pathology Source Type: research