Dose-dependent benzalkonium chloride toxicity imparts ocular surface epithelial changes with features of dry eye disease.

CONCLUSIONS: This study describes how exposing C57BL/6 mice to BAC induce some clinicopathological features of DED seen in humans, and therefore provides the foundations to explore the consequences on the ocular surface, particularly on limbal epithelia and its' stem cells. PMID: 31740391 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31740391?dopt=Abstract

Source: The Ocular Surface - November 14, 2019 Category: Opthalmology Authors: Zhang R, Park M, Richardson A, Tedla N, Pandzic E, de Paiva CS, Watson S, Wakefield D, Di Girolamo N Tags: Ocul Surf Source Type: research