Seroepidemiology Study of Helicobacter pylori Infection and Its Effect on Cardiovascular Diseases in Karaj, Iran.
Seroepidemiology Study of Helicobacter pylori Infection and Its Effect on Cardiovascular Diseases in Karaj, Iran. Monoclon Antib Immunodiagn Immunother. 2019 Nov 19;: Authors: Afsharpooyan S, Mohammadian T Abstract Helicobacter pylori infection occurs throughout the world between countries and races. A seroprevalence study of H. pylori infection in the occurrence of atherosclerosis (ASc) has been considered to be the main cause of cardiovascular diseases (CVDs) in part of Iran. From 600 volunteers, 97 serum samples were selected and tested for the presence of H. pylori infection. Positive and negative H. pylori infection samples were then selected for Chlamydia pneumonia and cytomegalovirus infection. Their serum levels for high-sensitive C-reactive protein (hs-CRP) and IL-6 titer were measured using an ELISA test. Prevalence of H. pylori infection was ∼68.04% in Karaj. Among the 22 samples of cytokine titration, 4 individuals were HP- and 18 were HP+. It was also noticed that 17 samples had normal titration (77.27%) of IL-6 and 3 had a high level of IL-6 (13.63%), 20 people had high hs-CRP titration (90.90%), and 2 were low level hs-CRP (9.1%). Obtained results showed that there is no significant difference between HP+ and HP- infection and IL-6 and hs-CRP titration. Results showed that H. pylori could not lead to ASc by increasing the levels of proinflammatory cytokines such as IL-6 and hs-CRP. Further studies are necessary for the detection of mech...
Abstract The use of live attenuated vaccine (LAV) is the main method for controlling infectious bronchitis (IB). It is advisable to develop a LAV using a dominant serotype in the region in the case of vaccine failure. Since 793/B serotype is one of the most predominant circulating IB viruses in Iran, attenuation of three Iranian 793/B isolates (IR/773/2001, IR/794/2002 and IR/520/2002) was done by serial passaging in specific pathogen free (SPF) embryonated chicken eggs up to 90 passages to assess the degree of their attenuation to achieve a native LAV in the future. Virulence and pathogenicity of passage levels 1...
Conclusion: The evidence from the present study suggests that T allele of CD33 rs3865444 polymorphism is associated with LOAD in the studied Iranian population. PMID: 31799158 [PubMed]
ConclusionsThe presence of Candida spp airway colonization is associated with longer durations of mechanical ventilation, higher 28-day mortality, higher ICU mortality, and probably longer ICU length of stay compared with the absence of colonization in patients with VAP.
Publication date: Available online 5 December 2019Source: Journal of Clinical and Experimental HepatologyAuthor(s): Waseem Amjad, Sandy Kotiah, Ankur Gupta, Michael Morris, Li Liu, Paul J. ThuluvathAbstractThe use of immunotherapy in transplant recipients is considered a contraindication because of very high risks for graft loss. The graft loss is to be expected since cytotoxic T-lymphocyte associated protein-4 (CTLA-4) and PD-1 pathways are implicated in graft tolerance. In this case report, we describe a woman with recurrent, disseminated hepatocellular carcinoma who was successfully treated with nivolumab, an immune checkpoint inhibitor.
Authors: George E, Rajalakshmi A Abstract Melioidosis is an infectious disease caused by gram negative bacterium Burkholderia pseudomallei. It is a soil and water pathogen and transmitted to humans through inoculation or inhalation. This disease is considered endemic in India and largely remains under reported. The most common presentation is pneumonia and bacteraemia, which can present acutely and as septic shock. Chronic presentation include-abscess, septic arthritis, osteomyelitis. The major risk factors are diabetes, liver disease, renal disease, chronic lung disease. In this article 18 cases have been reviewed...
Conclusion: Mosquitoes and midges have got a crucial role in the transmission of arboviruses. The risk of occurrence for the investigated arboviruses will continue depending upon many factors including the presence of these viruses in Turkey and its neighboring countries, uncontrolled livestock movements, global warming and climate changes. PMID: 31803784 [PubMed]
Conclusion: This study showed considerable values of acaricidal and repellent activity against Rh. bursa for both essential oils singly and in combination, so they can be considered as potent lethal/repellent agents for control of ticks, but more studies need for this purpose, study on lethal/repellent activity of these essential oils and/or other plants against other important arthropods can be considered as subjects for next experiments. PMID: 31803783 [PubMed]
Conclusion: Identity between samples and phylogenetic tree revealed that there is an extensive diversity range among isolates. Fifty percent of the isolates were under the risk of complicated malaria. Two of these patients (10%) needed special care and recovery was obtained after getting hospital services. PMID: 31803782 [PubMed]
Conclusion: Leishmania major is responsible for the most common CL in southern Iran. In addition, in two patients with L. major and L. tropica, mix infection with Crithidia was confirmed. The potential role of Crithidia as the main factor for CL and the probability of this parasite to have synergistic effects on Leishmania, as a hypothesis, requires more comprehensive researches on the ambiguity of this protozoon. PMID: 31803781 [PubMed]
Conclusion: Aedes species were a high density in borderline of Iran and Azerbaijan. Therefore, the north parts of Ardabil Province are a suitable habitat for Aedes species mosquitoes. Care should be taken for vector control in the case of occurrence of any arboviruses transmitted by Aedes mosquitoes. PMID: 31803780 [PubMed]