An ancestral vector improves on this year ’s model

Adenovirus associated virus (AAV) vectors are being increasingly used for gene therapy because they are not pathogenic in humans and persist for long periods in certain cell types. Currently 120 gene delivery clinical trials with these vectors are in progress, and two have been approved: Luxturna to treat a rare form of blindness, and another […]
Source: virology blog - Category: Virology Authors: Tags: Basic virology Information aav adenovirus-associated virus ancestral sequence reconstruction gene therapy in silico evolution vector viral Source Type: blogs